P
Paola Polchi
Researcher at University of Rome Tor Vergata
Publications - 98
Citations - 4763
Paola Polchi is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Thalassemia & Transplantation. The author has an hindex of 33, co-authored 98 publications receiving 4594 citations. Previous affiliations of Paola Polchi include University of Milan.
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Journal ArticleDOI
Bone Marrow Transplantation in Patients with Thalassemia
Guido Lucarelli,Maria Galimberti,Paola Polchi,Emanuele Angelucci,Donatella Baronciani,Claudio Giardini,Politi P,Durazzi Sm,Muretto P,F. Albertini +9 more
TL;DR: It is concluded that for patients under 16 years of age, transplantation of bone marrow from an HLA-identical donor offers a high probability of complication-free survival, particularly if they do not have hepatomegaly or portal fibrosis.
Journal ArticleDOI
Hepatic Iron Concentration and Total Body Iron Stores in Thalassemia Major
Emanuele Angelucci,Gary M. Brittenham,Christine E. McLaren,Marta Ripalti,Donatella Baronciani,Claudio Giardini,Maria Galimberti,Paola Polchi,Guido Lucarelli +8 more
TL;DR: The hepatic iron concentration is a reliable indicator of total body iron stores in patients with thalassemia major and in patientsWith transfusion-related iron overload, repeated determinations of the hepaticIron concentration can provide a quantitative means of measuring the long-term iron balance.
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Allogeneic Stem Cell Transplantation for Agnogenic Myeloid Metaplasia: A European Group for Blood and Marrow Transplantation, Société Française de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study
Philippe Guardiola,J E Anderson,Giuseppe Bandini,Francisco Cervantes,Volker Runde,William Arcese,Almalina Bacigalupo,Donna Przepiorka,Margaret R. O'Donnell,Paola Polchi,Agnès Buzyn,Laurent Sutton,Dominique Cazals-Hatem,George E. Sale,T. de Witte,Deeg Hj,Eliane Gluckman +16 more
TL;DR: Allogeneic stem cell transplantation is an effective treatment leading to cure in a substantial number of patients with AMM and a better characterization of the variables affecting the posttransplant outcome should lead to a decreased transplant-related mortality and an improvement in results.
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Marrow transplantation for thalassaemia following busulphan and cyclophosphamide.
Guido Lucarelli,Paola Polchi,M Galimberti,T Izzi,C Delfini,M Manna,F Agostinelli,Donatella Baronciani,C. Giorgi,Emanuele Angelucci +9 more
TL;DR: 30 patients with homozygous beta-thalassaemia received allogeneic marrow transplants following busulphan (Bu) and cyclophosphamide (Cy) and post-transplant immunosuppression was with methotrexate (MTX) or MTX and Cy.
Journal ArticleDOI
Marrow Transplantation in Patients with Thalassemia Responsive to Iron Chelation Therapy
Guido Lucarelli,Maria Galimberti,Paola Polchi,Emanuele Angelucci,Donatella Baronciani,Claudio Giardini,Marco Andreani,F Agostinelli,F. Albertini,Reginald A. Clift +9 more
TL;DR: The high probability of cure with little early or late morbidity and mortality suggests that patients with class 1 thalassemia who have HLA-identical donors available should be treated by bone marrow transplantation.