Paola Venier

TL;DR: The results support the proposal of BPH, AChE, DTD and CAT activities as suitable biomarkers of PAH exposure for these sentinel species and demonstrate the neurotoxicity and the genotoxicity of B[a]P exposure in the mussel.

TL;DR: The random amplified polymorphic DNA (RAPD) assay and related techniques like the arbitrarily primed polymerase chain reaction (AP-PCR) have been shown to detect genotoxin-induced DNA damage and mutations but further research is required to better understand the potential and limitations of the RAPD assay.

TL;DR: In this article, Mediterranean mussels were exposed to benzo[a]pyrene for two days at doses which had previously caused the formation of specific adducts in gill DNA.

TL;DR: The Mytibase collection is rich in gene transcripts modulated in response to antigenic stimuli and represents an interesting window for looking at the mussel immunome (transcriptomes mediating the mussels response to non-self or abnormal antigens).

TL;DR: The formation of DNA adducts, the evidence of oxidative DNA damage, and changes in CYP1A-immunopositive protein levels support the hypothesis that B[a]P can induce DNA damage in mussels through a number of different molecular mechanisms.