Paolo Spinella

TL;DR: The measurements of cortisol and related compound levels in blood, urine and saliva used to study the physiological and pathological cortisol involvement, are critically reviewed and the immunoassay and chromatographic methods for cortisol measurement in the various biological fluids are examined.

TL;DR: The most important results show how polyphenolic compounds are able to inhibit the expression and the release of a number of pro-inflammatory mediators and proteolytic enzymes, the activity of different transcriptional factors and the production of reactive oxygen species in vitro.

TL;DR: A functional and basic method for the quantitative analysis of urine cortisol (F) and cortisone (E) using a Solid-Phase Extraction column and HPLC with ultraviolet detection is described and validated to analyse urine samples to study F and E relation and ratio in athletes and healthy sedentary subjects.

TL;DR: It is suggested that licorice can reduce fat by inhibiting 11β-hydroxysteroid dehydrogenase Type 1 at the level of fat cells by reducing body fat mass and suppressing aldosterone.

TL;DR: Although some aspects concerning the mechanisms of action through which the Mediterranean diet pattern exerts its beneficial effects remain to be elucidated, arthritis patients may potentially benefit from it in view of their increased cardiovascular risk and the treatment they require which may have side effects.