Showing papers in "Clinical Biochemistry in 2009"

TL;DR: It is concluded that the revised VIM is of primordial importance for good understanding within and between the measurement communities worldwide.

TL;DR: Overall, growing evidence suggests that hepatic insulin resistance is sufficient to induce several components of the metabolic syndrome and promote progression to cardiovascular disease.

TL;DR: The particular importance of early prediction and the integral role that point-of-care (POC) testing is expected to play in the future of cardiac care is critically discussed.

TL;DR: As with baseline 25( OH)D, T436K genotype predicts 25(OH)D changes after long-term vitamin D supplementation.

TL;DR: The DiaSorin LIAISON 25 OH Vitamin D TOTAL assay is an accurate and precise automated tool for serum total 25(OH)D determination.

TL;DR: Saudi autistic children are under H( 2)O(2) stress due to GSH depletion, over expression of SOD together with the unchanged catalase enzyme, which could be helpful in the early diagnosis of young autistic patients and suggesting the possibility of antioxidant supplementation for the early intervention with autistic children.

TL;DR: Bone turnover markers (BTMs) measure the rate of bone remodelling allowing for a dynamic assessment of skeletal status and hold promise in identifying those at highest risk of rapid bone loss and subsequent fracture.

TL;DR: The authors' set of depressive women was characterized by changes indicating an increased oxidative stress, as well as by certain features of metabolic syndrome.

TL;DR: The measurements of cortisol and related compound levels in blood, urine and saliva used to study the physiological and pathological cortisol involvement, are critically reviewed and the immunoassay and chromatographic methods for cortisol measurement in the various biological fluids are examined.

TL;DR: Hypercholesterolemia is associated with an increase in inflammatory and oxidative stress biomarkers, and it also reduces the capacity of albumin to bind cobalt owing to ischemia, resulting in an increased IMA.

TL;DR: The greater levels of cytokine and growth factor expression in the DDD group than in the HNP explain why discogenic patients usually have more severe back pain than patients with herniated discs.

TL;DR: This study has confirmed an imbalance in the oxidative stress/antioxidant status and revealed an altered nitrosative status in prostate cancer patients.

TL;DR: The biochemical perspectives of continuous glucose monitoring and its clinical use in type 1 diabetes are reviewed, showing a reduction in glycated hemoglobin and glycemic variability.

TL;DR: DFI, HDS% and round-head sperms are increased in idiopathic infertile men; this increase is associated with cigarette smoking.

TL;DR: The group of laboratories, one of the leading institutions in the area, had previous experience with ISO 9001 and ISO 17025 Accreditation at non-medical sections and were certified in March, 2007.

TL;DR: It is demonstrated that all purine compounds, including uric acid, are elevated in biological fluids of MS patients, corroborating the notion of sustained purine catabolism, possibly due to imbalance in ATP homeostasis, under these pathological conditions.

TL;DR: Key issues concerning the implementation of a metrologically-correct approach for result standardization are: 1) the clear definition of the clinically allowable error of measurements and 2) the post-market surveillance of the performance of IVD products.

TL;DR: The present review raises particular attention to the present-day deficiencies in available pediatric reference intervals, and highlights the special issues and unique difficulties that are additionally faced when establishing reference intervals in children.

TL;DR: Investigating alterations in lipid profiles and in the serum concentrations of acylated and desacylated ghrelin, paraoxonase and arylesterase in psychiatric patients found they may be involved in the etiology of depressive disorders.

TL;DR: Investigation of the association of parental hyperhomocysteinemia, paternal age, paternal C677T MTHFR polymorphism and DNA damage with recurrent pregnancy loss found they are risk factors for RPL.

TL;DR: These ci8200 method specific reference intervals not only provide robust intervals for users of this system but are also useful for any laboratory requiring pediatric intervals if they can be shown to be transferable and if validated for the local patient population.

TL;DR: Genetic factors both related and unrelated to the beta- and alpha-globin gene clusters, iron metabolism, endocrinological disorders, and some types of anemia, together with intra- and inter-laboratory variations in HbA(2) determination, may cause difficulties in evaluating this measurement in screening programs for hemoglobinopathies.

TL;DR: Higher blood levels of beta-HCH may be associated with risk of preterm labor, and a statistically significant relation was observed between preterm birth and beta- HCH levels only.

TL;DR: Osteopontin may serve as a biochemical marker for determining disease severity and could be predictive of prognosis with respect to the progression of knee OA.

TL;DR: This fast assay can be used in low respiratory tract infections and has high correlation with the manual assay, B.A.R.H.M.S MR-proADM KRYPTOR, which is a homogeneous assay.

TL;DR: An improved, high throughput, cost-effective method for drugs of abuse screening has been implemented and is a viable alternative to the previous immunoassay method.

TL;DR: A reliable assay using a non-toxic substrate for the measurement of serum lactonase activity and a lower influence of genetic polymorphisms than the classical assay using paraoxon are reported.

TL;DR: ACD and CTAD are appropriate anticoagulants for PRP production and were superior to heparin and citrate in maintaining the integrity of platelet structures and preventing the platelet spontaneous activation.

TL;DR: Plasma levels of sRAGE are significantly reduced in definite and borderline NASH and inversely correlated with ALT and AST, respectively.

TL;DR: The present study confirmed the impairment of energy metabolism in Saudi autistic patients which could be correlated to the oxidative stress previously recorded in the same investigated samples.