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Parijat Sengupta

Researcher at University of Illinois at Urbana–Champaign

Publications -  28
Citations -  2004

Parijat Sengupta is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Optogenetics & Fluorescence correlation spectroscopy. The author has an hindex of 15, co-authored 28 publications receiving 1844 citations. Previous affiliations of Parijat Sengupta include Tata Institute of Fundamental Research & Washington State University.

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Measuring fast dynamics in solutions and cells with a laser scanning microscope.

TL;DR: Novel extensions to ICS are developed that probe spatial correlations in previously inaccessible temporal windows and are used to determine for the first time spatially resolved diffusions of paxillin-EGFP stably expressed in CHOK1 cells.
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Fluctuation correlation spectroscopy with a laser-scanning microscope: exploiting the hidden time structure.

TL;DR: The analysis used to process laser-scanning images of solutions and cells to obtain molecular diffusion constant in the microsecond to second timescale is described.
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Measuring size distribution in highly heterogeneous systems with fluorescence correlation spectroscopy.

TL;DR: A Maximum Entropy Method based fitting routine (MEMFCS) is introduced that analyzes FCS data in terms of a quasicontinuous distribution of diffusing components, and also guarantees a maximally wide distribution that is consistent with the data.
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Optogenetic skeletal muscle-powered adaptive biological machines

TL;DR: A modular light-controlled skeletal muscle-powered bioactuator that can generate up to 300 µN (0.56 kPa) of active tension force in response to a noninvasive optical stimulus is created, setting the stage for developing multicellular bio-integrated machines and systems for a range of applications.
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The Amyloid β Peptide (Aβ1-40) Is Thermodynamically Soluble at Physiological Concentrations†

TL;DR: Using fluorescence correlation spectroscopy, Wang et al. as mentioned in this paper showed that Aβ1-40 precipitates in vitro only if the dissolved concentration is > 14 μM, after which the size distribution of Aβ monomer/oligomers in the solution phase becomes stationary in time and independent of the starting Aβ concentration.