Pasquale Piccinni

TL;DR: Mortality among critically ill patients with acute renal failure was high, but increase in the rate of ultrafiltration improved survival significantly, and it is recommended thatUltrafiltration should be prescribed according to patient's bodyweight and should reach at least 35 mL h(-1) kg(-1).

TL;DR: Plasma NGAL is a useful early marker for AKI in a heterogeneous adult ICU population, in which the timing of renal insult is largely unknown, and it predicts need for RRT and correlates with AKI severity.

TL;DR: Independent risk factors for mortality included RIFLE class, sepsis, and need for renal replacement therapy, whereas a postsurgical cause of AKI, exposure to nephrotoxins, higher serum creatinine, and urine output were associated with lower mortality risk.

TL;DR: Different RRT techniques are available in most centres, but a general lack of treatment dose standardization is noted by a survey, and new classifications such as RIFLE criteria might improve well-known uncertainty about ARF definition.

TL;DR: In patients with septic shock, coupled plasmafiltration-adsorption combined with hemodialysis was associated with improved hemodynamics compared with continuous venovenous hemodiafiltration, suggesting a potential role for blood purification in the treatment of septicshock.