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Patricia A. Johnson

Researcher at Dublin City University

Publications -  21
Citations -  580

Patricia A. Johnson is an academic researcher from Dublin City University. The author has contributed to research in topics: Virus & Antigen. The author has an hindex of 12, co-authored 21 publications receiving 504 citations. Previous affiliations of Patricia A. Johnson include Belfast City Hospital & Maynooth University.

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Effect of anaesthetic technique on the natural killer cell anti-tumour activity of serum from women undergoing breast cancer surgery: a pilot study.

TL;DR: Serum from women with breast cancer undergoing surgical excision who were randomized to receive a PPA anaesthetic technique led to greater human donor NK cell cytotoxicity in vitro compared with serum from women who received GA.
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Plasmid DNA encoding influenza virus haemagglutinin induces Th1 cells and protection against respiratory infection despite its limited ability to generate antibody responses.

TL;DR: Induction and maintenance of antibody and T cell subtypes with different doses of naked DNA encoding the haemagglutinin (HA) gene of influenza virus were examined and compared to the immune responses and protection induced by respiratory tract infection and immunization with a killed virus vaccine.
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Wild-Type Gross Leukemia Virus: Classification of Soluble Antigens (GSA)

TL;DR: By inhibiting techniques using indirect immunofluorescence tests and indirect immunoelectron microscopy, the G(Gross) soluble antigens (GSA) in the body fluids of AKR and C58 mice, which have a high incidence of spontaneous leukemia, were classified according to the known specificity of G antigen in the murine Gross leukemia system.
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Up‐regulation of the endothelial cell adhesion molecule intercellular adhesion molecule‐1 (ICAM‐1) by autoantibodies in autoimmune vasculitis

TL;DR: The capacity of ANCA and ANA‐positive sera to up‐regulate adhesion molecules on endothelial cells may be a factor in the vessel wall inflammation seen in ANCA‐associated vasculitis.
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Innate IL-10 promotes the induction of Th2 responses with plasmid DNA expressing HIV gp120

TL;DR: The findings suggest that T cell responses induced by DNA vaccines is influenced by the nature of the antigen, and that the induction of Th2-biased responses with gp120pDNA is mediated in part through the stimulation of innate IL-10, which inhibits activation of DCs that direct the inductionof Th1 cells.