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Patricia L. Lakin-Thomas
Researcher at York University
Publications - 38
Citations - 1481
Patricia L. Lakin-Thomas is an academic researcher from York University. The author has contributed to research in topics: Neurospora crassa & Circadian clock. The author has an hindex of 20, co-authored 38 publications receiving 1442 citations. Previous affiliations of Patricia L. Lakin-Thomas include University of Cambridge.
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Control of respiration and oxidative phosphorylation in isolated rat liver cells
TL;DR: There was a unique relationship between respiration and membrane potential irrespective of the ATP content of the cells indicating thatosphorylation potential controls respiration solely via phosphorylation (rather than by controlling NADH supply).
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Circadian rhythms in Neurospora crassa: biochemistry and genetics.
TL;DR: In this article, the Circadian Rhythms in Neurospora crassa: Biochemistry and Genetics, Vol. 17, No. 5, pp. 365-416.
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Transcriptional Feedback Oscillators: Maybe, Maybe Not...
TL;DR: The weight of anomalies is now so large that the standard transcription/translation mechanism is no longer an adequate model for circadian oscillators, and a circadian system that uses a noncircadian oscillator consisting of metabolic feedback loops is most useful.
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Amplitude model for the effects of mutations and temperature on period and phase resetting of the Neurospora circadian oscillator.
TL;DR: This paper analyzes published and unpublished data on phase resetting of the circadian oscillator in the fungus Neurospora crassa and demonstrates a correlation between period and resetting behavior in several mutants with altered periods, raising the possibility that amplitude changes are a general phenomenon in circadian oscillators.
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Circadian rhythms: new functions for old clock genes
TL;DR: The mechanisms of circadian clocks, which time daily events, are being investigated by characterizing 'clock genes' that affect daily rhythms by describing the core of the clock mechanism by a transcription-translation feedback-loop model.