P
Patricia P. Wilkins
Researcher at Centers for Disease Control and Prevention
Publications - 110
Citations - 6785
Patricia P. Wilkins is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Taenia solium & Neurocysticercosis. The author has an hindex of 42, co-authored 110 publications receiving 6200 citations. Previous affiliations of Patricia P. Wilkins include Oklahoma Medical Research Foundation & University of Oklahoma Health Sciences Center.
Papers
More filters
Journal ArticleDOI
Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene
TL;DR: A real-time PCR assay using a TaqMan probe targeting lipL32, which is present only in pathogenic Leptospira spp, with high specificity and sensitivity may prove to be a rapid method for diagnosing acute leptospirosis.
Journal ArticleDOI
Post-translational Modifications of Recombinant P-selectin Glycoprotein Ligand-1 Required for Binding to P- and E-selectin
Fugang Li,Patricia P. Wilkins,Suzanne C. Crawley,Jasminder Weinstein,Richard D. Cummings,Rodger P. McEver +5 more
TL;DR: It is demonstrated that PSGL-1 requires core 2 O-linked glycans that are sialylated and fucosylated to bind P- and E-selectin.
Journal ArticleDOI
Tyrosine Sulfation of P-selectin Glycoprotein Ligand-1 Is Required for High Affinity Binding to P-selectin (∗)
TL;DR: It is demonstrated that PSGL-1 synthesized in human HL-60 cells can be metabolically labeled with [S]sulfate that is incorporated primarily into tyrosine sulfate, resulting in a concordant decrease in binding to P-selectin.
Journal ArticleDOI
Evaluation of Three Commercial Assays for Detection of Giardia and Cryptosporidium Organisms in Fecal Specimens
Stephanie P. Johnston,Melissa M. Ballard,Michael J. Beach,Louise M. Causer,Patricia P. Wilkins +4 more
TL;DR: One of these rapid diagnostic tests, the ImmunoCard STAT! lateral-flow immunoassay, was compared with the MERIFLUOR direct fluorescent-antibody (DFA) test, the Pro SpecT EZ microplate assay for Giardia and the ProSpecT microplate assays for Cryptosporidium, and modified Kinyoun's acid-fast stained smears for the detection of Cryptospora.
Journal ArticleDOI
Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells
TL;DR: The structures of the Ser/Thr-linked O-glycans of PSGL-1 synthesized by HL-60 cells metabolically radiolabeled with 3H-sugar precursors are described and demonstrated to be critical for high affinity interactions between PS GL-1 and selectins.