Patricia Soares de Oliveira-Szejnfeld

TL;DR: Combined findings from clinical, laboratory, imaging, and pathological examinations provided a more complete picture of the severe damage and developmental abnormalities caused by ZIKV infection than has been previously reported.

TL;DR: The spectrum of findings associated with congenital Zika virus infections in the IPESQ in northeastern Brazil is illustrated to aid the radiologist in identifying Zika virus infection at imaging.

TL;DR: A comprehensive neuropathological study in ten newborn babies infected with ZIKV during pregnancy, including the spinal cords and dorsal root ganglia, and also muscle, pituitaries, eye, systemic organs, and placentas, indicates a developmental vulnerability of the immature CNS, and sheds light on possible mechanisms of brain injury of this newly recognized public health threat.

TL;DR: Polyfunctional immune activation associated with increased interferon‐gamma‐inducible protein 10, interleukin (IL)‐6, IL‐8, vascular endothelial growth factor (VEGF), monocyte chemoattractive protein 1 (MCP‐1), and granulocyte colony‐stimulating factor (G‐CSF) levels in the amniotic fluid of ZIKV‐positive pregnant women with neonatal microcephaly are reported.

TL;DR: Different neurological profiles in the congenital Zika syndrome spectrum are described, with functional outcomes tending to correlate with these groups, including predominant symptom complexes and comorbidities in toddlers and preschoolers.