P
Patrick L Chow
Researcher at Bristol-Myers Squibb
Publications - 16
Citations - 1225
Patrick L Chow is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Imaging phantom & Correction for attenuation. The author has an hindex of 9, co-authored 14 publications receiving 1145 citations. Previous affiliations of Patrick L Chow include University of California, Los Angeles.
Papers
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Journal Article
Performance Evaluation of the microPET Focus: A Third-Generation microPET Scanner Dedicated to Animal Imaging
Yuan-Chuan Tai,Ananya Ruangma,Douglas J. Rowland,Stefan Siegel,D.F. Newport,Patrick L Chow,Richard Laforest +6 more
TL;DR: The microPET Focus has significantly improved performance over the previous models in all areas evaluated and is expected to advance the potential of small animal PET.
Journal Article
Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging.
Christophe Deroose,Abhijit De,Andreas M. Loening,Patrick L Chow,Pritha Ray,Arion F. Chatziioannou,Sanjiv S. Gambhir +6 more
TL;DR: The combination of 18F-FHBG PET, small-animal CT, and BLI allows a sensitive and improved quantification of tumor burden in mice and is potentially useful for the study of the biologic determinants of metastasis and for the evaluation of novel cancer treatments.
Journal ArticleDOI
Attenuation correction for small animal PET tomographs
TL;DR: Results indicate that the scale factor method of attenuation correction places the average measured activity concentration about the expected value, without correcting for the cupping artefact from attenuation.
Journal ArticleDOI
Synthesis and Biologic Evaluation of a Novel 18F-Labeled Adnectin as a PET Radioligand for Imaging PD-L1 Expression
David J. Donnelly,R. Adam Smith,Paul E. Morin,Dasa Lipovsek,Jochem Gokemeijer,Daniel Cohen,Virginie Lafont,Tritin Tran,Erin L. Cole,Martin C. Wright,Joonyoung Kim,Adrienne Pena,Daniel W. Kukral,Douglas D. Dischino,Patrick L Chow,Jinping Gan,Olufemi Adelakun,Xi-Tao Wang,Kai Cao,David Leung,Samuel J. Bonacorsi,Wendy Hayes +21 more
TL;DR: The feasibility of noninvasively imaging the PD-L1 status of tumors by small-animal PET studies is demonstrated by 18F-BMS-986192, which bound to tumor tissues as a function of PD- L1 expression determined by immunohistochemistry.
Journal ArticleDOI
Monte carlo simulations of dose from microCT imaging procedures in a realistic mouse phantom.
TL;DR: The purpose of this work was to calculate radiation dose and its organ distribution in a realistic mouse phantom from micro-computed tomography (microCT) imaging protocols using GATE and a voxelized, realistic phantom.