D
David Leung
Researcher at Bristol-Myers Squibb
Publications - 43
Citations - 1415
David Leung is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Nivolumab & Medicine. The author has an hindex of 15, co-authored 38 publications receiving 916 citations. Previous affiliations of David Leung include Columbia University.
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Journal ArticleDOI
Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer
Anna-Larissa N. Niemeijer,David Leung,Marc C. Huisman,Idris Bahce,Otto S. Hoekstra,G.A.M.S. (Guus) van Dongen,Ronald Boellaard,Shuyan Du,Wendy Hayes,Ralph Adam Smith,Albert D. Windhorst,N.H. Hendrikse,Alex J. Poot,Danielle J. Vugts,Erik Thunnissen,Paul E. Morin,Dasa Lipovsek,David J. Donnelly,Samuel J. Bonacorsi,Linda M. Velasquez,T.D. de Gruijl,Egbert F. Smit,A.J. de Langen,A.J. de Langen +23 more
TL;DR: The authors assess the clinical toxicity, safety and quality of non-invasive imaging of PD-1 and PD-L1 expression in 13 patients with advanced lung cancer prior to treatment with immunotherapy and show it correlates with response.
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Cyclodextrin dimers as cleavable carriers of photodynamic sensitizers.
TL;DR: Several phthalocyanines carrying hydrophobic components have been synthesized and shown to bind to a group of cyclodextrin dimers with a carbon-carbon double bond in the linker, which has useful potential in photodynamic therapy.
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Synthesis and Biologic Evaluation of a Novel 18F-Labeled Adnectin as a PET Radioligand for Imaging PD-L1 Expression
David J. Donnelly,R. Adam Smith,Paul E. Morin,Dasa Lipovsek,Jochem Gokemeijer,Daniel Cohen,Virginie Lafont,Tritin Tran,Erin L. Cole,Martin C. Wright,Joonyoung Kim,Adrienne Pena,Daniel W. Kukral,Douglas D. Dischino,Patrick L Chow,Jinping Gan,Olufemi Adelakun,Xi-Tao Wang,Kai Cao,David Leung,Samuel J. Bonacorsi,Wendy Hayes +21 more
TL;DR: The feasibility of noninvasively imaging the PD-L1 status of tumors by small-animal PET studies is demonstrated by 18F-BMS-986192, which bound to tumor tissues as a function of PD- L1 expression determined by immunohistochemistry.
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Single Institution Experience with Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) for the Primary Prevention of Lymphedema.
Sheldon Feldman,Hannah Bansil,Jeffrey A. Ascherman,Robert T Grant,Billie Borden,Peter W. Henderson,Adewuni Ojo,Bret Taback,Margaret Chen,P Ananthakrishnan,Amiya Vaz,Fatih Levent Balci,Fatih Levent Balci,Chaitanya R. Divgi,David Leung,Christine H. Rohde +15 more
TL;DR: Early data show that LYMPHA is feasible, safe, and effective for the primary prevention of breast cancer-related lymphedema, and this technique was described by Boccardo, Campisi in 2009.
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Diagnostic Performance of 4D CT and Sestamibi SPECT/CT in Localizing Parathyroid Adenomas in Primary Hyperparathyroidism.
Randy Yeh,Yu-Kwang Donovan Tay,Gaia Tabacco,Laurent Dercle,Jennifer H Kuo,Leonardo Bandeira,Catherine McManus,David Leung,James A. Lee,John P. Bilezikian +9 more
TL;DR: Four-dimensionalCT provided superior preoperative localization compared with sestamibi SPECT/CT in patients with single and multigland disease, and the combination of the two modalities did not improve diagnostic performance compared with four-dimensional CT alone.