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Paul Bourgine
Researcher at Lund University
Publications - 102
Citations - 6924
Paul Bourgine is an academic researcher from Lund University. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 28, co-authored 99 publications receiving 6376 citations. Previous affiliations of Paul Bourgine include University Hospital of Basel & Université Paris-Saclay.
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Proceedings Article
Distributed Optimization by Ant Colonies
TL;DR: A distributed problem solving environment is introduced and its use to search for a solution to the travelling salesman problem is proposed.
Journal ArticleDOI
Topological and causal structure of the yeast transcriptional regulatory network.
TL;DR: A graph of 909 genetically or biochemically established interactions among 491 yeast genes is created, showing a deviation from randomness probably reflects functional constraints that include biosynthetic cost, response delay and differentiative and homeostatic regulation.
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Cell Lineage Reconstruction of Early Zebrafish Embryos Using Label-Free Nonlinear Microscopy
Nicolas Olivier,Miguel Luengo-Oroz,Louise Duloquin,Emmanuel Faure,Thierry Savy,Israel Veilleux,Xavier Solinas,Delphine Débarre,Paul Bourgine,Andres Santos,Nadine Peyriéras,Emmanuel Beaurepaire +11 more
TL;DR: A framework for imaging and reconstructing unstained whole zebrafish embryos for their first 10 cell division cycles is designed and measurements along the cell lineage are reported with micrometer spatial resolution and minute temporal accuracy.
Journal ArticleDOI
Engineering of a functional bone organ through endochondral ossification.
Celeste Scotti,Elia Piccinini,Hitoshi Takizawa,Atanas Todorov,Paul Bourgine,Adam Papadimitropoulos,Andrea Barbero,Markus G. Manz,Ivan Martin +8 more
TL;DR: The generation by appropriately instructed hMSC of an ectopic “bone organ” with a size, structure, and functionality comparable to native bones is reported, providing a model useful for fundamental and translational studies of bone morphogenesis and regeneration, as well as for the controlled manipulation of hematopoietic stem cell niches in physiology and pathology.