P
Paul Coucke
Researcher at Ghent University
Publications - 238
Citations - 13452
Paul Coucke is an academic researcher from Ghent University. The author has contributed to research in topics: Pseudoxanthoma elasticum & Gene. The author has an hindex of 55, co-authored 212 publications receiving 11905 citations. Previous affiliations of Paul Coucke include Ghent University Hospital & Baylor College of Medicine.
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Journal ArticleDOI
Added Value of Infrared, Red-free and Autofluorescence Fundus Imaging in Pseudoxanthoma Elasticum
Julie De Zaeytijd,Olivier Vanakker,Paul Coucke,Anne De Paepe,Jean-Jacques De Laey,Bart P. Leroy +5 more
TL;DR: Infrared, red-free and autofluorescence imaging are more sensitive than white light funduscopy and imaging in visualising early retinal signs of PXE, and increases the chances of making a correct diagnosis early, and aids in the accurate evaluation of evolution of disease in the ophthalmic follow-up of PxE patients.
Journal ArticleDOI
Audiologic phenotype of osteogenesis imperfecta: use in clinical differentiation.
Freya Swinnen,Ingeborg Dhooge,Paul Coucke,Patrizia D'Eufemia,Francesco Zardo,Ton J. T. M. Garretsen,Cor W. R. J. Cremers,Els De Leenheer +7 more
TL;DR: The hearing loss in OI may initiate at a young age and is progressive, however, the rate of progression, as well as the hearing loss severity, onset, and configuration depend on the type of hearing loss, which may be conductive/mixed or pure sensorineural.
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Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos
Thomas Naert,Dieter Tulkens,Nicole A. Edwards,Marjolein Carron,Nikko-Ideen Shaidani,Marcin Wlizla,Annekatrien Boel,Suzan Demuynck,Marko E. Horb,Paul Coucke,Andy Willaert,Aaron M. Zorn,Kris Vleminckx +12 more
TL;DR: It is shown that a publicly available neural network previously trained in mouse embryonic stem cell cultures (InDelphi-mESC) is able to accurately predict CRISPR/Cas9 gene editing outcomes in early vertebrate embryos.
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Glucose transporter type 10—lacking in arterial tortuosity syndrome—facilitates dehydroascorbic acid transport
Csilla E. Németh,Paola Marcolongo,Alessandra Gamberucci,Rosella Fulceri,Angiolo Benedetti,Nicoletta Zoppi,Marco Ritelli,Nicola Chiarelli,Marina Colombi,Andy Willaert,Bert Callewaert,Paul Coucke,Pál Gróf,Szilvia K. Nagy,Tamás Mészáros,Gábor Bánhegyi,Éva Margittai +16 more
TL;DR: It is demonstrated that GLUT10 is a DAA transporter and DAA transport is diminished in the endomembranes of fibroblasts from ATS patients.
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Congenital fixed dilated pupils due to ACTA2- multisystemic smooth muscle dysfunction syndrome.
Françoise Roulez,Fran Faes,Patricia Delbeke,Patrick Van Bogaert,Georges Rodesch,Julie De Zaeytijd,Fanny Depasse,Paul Coucke,Françoise Meire +8 more
TL;DR: Congenital fixed dilated pupils is a rare condition and should alert ophthalmologists to the possibility of the coexistence of systemic life-threatening disorders.