P
Paul Coucke
Researcher at Ghent University
Publications - 238
Citations - 13452
Paul Coucke is an academic researcher from Ghent University. The author has contributed to research in topics: Pseudoxanthoma elasticum & Gene. The author has an hindex of 55, co-authored 212 publications receiving 11905 citations. Previous affiliations of Paul Coucke include Ghent University Hospital & Baylor College of Medicine.
Papers
More filters
Journal ArticleDOI
Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome.
Sarah Delbaere,Tim Van Damme,Delfien Syx,Sofie Symoens,Paul Coucke,Andy Willaert,Fransiska Malfait +6 more
TL;DR: It is shown that in early development the human spEDS-B4GALT7 phenotype is faithfully mimicked in these zebrafish models, which underscore a key role for β4GalT7 inEarly development of cartilage, bone and muscle.
Journal ArticleDOI
X-linked liver glycogenosis: localization and isolation of a candidate gene
Jan Hendrickx,Paul Coucke,P. Bossuyt,Jan Wauters,P Raeymaekers,F Marchau,G. Peter,A Smit,[No Value] Stolte,Ib Sardharwalla,J Berthelot,[No Value] Vandenbergh,Rudolphus Berger,C Vanbroeckhoven,C Baussan,M Wapenaar,J Fernandes,P. J. Willems +17 more
TL;DR: It is shown that the rabbit liver alpha subunit of PHK (PHKA2) hybridizes to human Xp22, which most probably harbours the mutation(s) responsible for XLG and a human PHKA2 cDNA from a human hepatoma lambda gt11 cDNA library is isolated.
Journal Article
Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families
Bert Callewaert,Annelore Willaert,Wilhelmina S. Kerstjens-Frederikse,J. De Backer,Koenraad Devriendt,Beate Albrecht,Maria A. Ramos-Arroyo,Martine Doco-Fenzy,R Hennekam,Reed E. Pyeritz,G Gillessen-Kaesbach,Emma Wakeling,Serena Nik-Zainal,Christine Francannet,P Mauran,C Booth,M Barrow,Paul Coucke,Bart Loeys,A. De Paepe +19 more
TL;DR: The natural history of ATS in this series was less severe than previously reported, but it does indicate a risk for ischemic events and overt diabetes is not related to SLC2A10 mutations associated with ATS.
Journal ArticleDOI
Reassessment of causality of ABCC6 missense variants associated with pseudoxanthoma elasticum based on Sherloc.
Shana Verschuere,Shana Verschuere,Nastassia Navassiolava,Ludovic Martin,Pasi I. Nevalainen,Paul Coucke,Paul Coucke,Olivier Vanakker,Olivier Vanakker +8 more
TL;DR: The results emphasize the need for segregation analysis, functional assays, and detailed evidence sharing in variant databases to reach a confident interpretation of ABCC6 missense variants and subsequent appropriate genetic and preconceptual counseling.
Journal ArticleDOI
The Soft Tissue Immunologic Response to Hydroxyapatite-Coated Transmucosal Implant Surfaces: A Study in Humans
Elisabeth A. W. J. De Wilde,Ryo Jimbo,Ann Wennerberg,Yoshihito Naito,Yoshihito Naito,Paul Coucke,Matthew Bryington,Stefan Vandeweghe,Hugo De Bruyn,Hugo De Bruyn +9 more
TL;DR: Nano-hydroxyapatite-coated surfaces in the transmucosal region yielded similar inflammatory response and is suggested to be as biocompatible as commercially pure titanium surfaces.