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Paul L. A. M. Corstjens
Researcher at Leiden University
Publications - 65
Citations - 3579
Paul L. A. M. Corstjens is an academic researcher from Leiden University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 30, co-authored 45 publications receiving 3245 citations. Previous affiliations of Paul L. A. M. Corstjens include New York University & Leiden University Medical Center.
Papers
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Journal ArticleDOI
Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: a rapid, sensitive DNA test to identify human papillomavirus type 16 infection.
Paul L. A. M. Corstjens,Michel Zuiderwijk,Antoinette A. T. P. Brink,Shang Li,Hans H. Feindt,R. Sam Niedbala,Hans J. Tanke +6 more
TL;DR: The sensitivity of UPT detection in these complex mixtures indicates that detection of viral infections without PCR or other amplification technique is achievable and provides a rapid alternative for more elaborate gel electrophoresis and Southern blotting.
Journal ArticleDOI
An integrated, self-contained microfluidic cassette for isolation, amplification, and detection of nucleic acids
Dafeng Chen,Michael G. Mauk,Xianbo Qiu,Changchun Liu,Jitae Kim,Sudhir Ramprasad,Serge Ongagna,William R. Abrams,Daniel Malamud,Paul L. A. M. Corstjens,Haim H. Bau +10 more
TL;DR: The cassette and actuator described here can be used to detect other diseases as well as the presence of bacterial and viral pathogens in the water supply and other fluids.
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Mucins and molluscan calcification. Molecular characterization of mucoperlin, a novel mucin-like protein from the nacreous shell layer of the fan mussel Pinna nobilis (Bivalvia, pteriomorphia).
Frédéric Marin,Paul L. A. M. Corstjens,Béatrice de Gaulejac,Elizabeth de Vrind-De Jong,Peter Westbroek +4 more
TL;DR: This is the first paper reporting the cloning of a molluscan mucin and the first molecular evidence for the involvement of a mucin in mollusk calcification, and proposes the name mucoperlin.
Journal ArticleDOI
cumA, a gene encoding a multicopper oxidase, is involved in Mn2+ oxidation in Pseudomonas putida GB-1.
G. J. Brouwers,Johannes P. M. de Vrind,Paul L. A. M. Corstjens,Pierre Cornelis,Christine Baysse,Elisabeth W. de Vrind-de Jong +5 more
TL;DR: Data indicate that the multicopper oxidase CumA is involved in the oxidation of Mn2+ and that CumB is required for optimal growth of P. putida GB-1-002 and that the cumA mutation may have a polar effect on cumB.
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Up-Converting Phosphor Technology-Based Lateral Flow Assay for Detection of Schistosoma Circulating Anodic Antigen in Serum
Paul L. A. M. Corstjens,Lisette van Lieshout,Michel Zuiderwijk,Dieuwke Kornelis,Hans J. Tanke,André M. Deelder,Govert J. van Dam +6 more
TL;DR: The UPT-LF assay is a low-complexity test with higher sensitivity than the CAA-ELISA, well suited for laboratory diagnosis of individual active Schistosoma infections.