Metalated heterocycles and their applications in synthetic organic chemistry.

Deep Sea Adriana Lorente,†,‡ Janire Lamariano-Merketegi,†,‡ Fernando Albericio,†,‡,§,# and Mercedes Álvarez*,†,‡,⊥ †Institute for Research in Biomedicine, Barcelona Science Park, University of Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain ‡CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain Department of Organic Chemistry, University of Barcelona, 08028 Barcelona, Spain School of Chemistry, University of KwaZulu-Natal, 4001-Durban, South Africa Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain

Tetrahydrofuran-containing macrolides: a fascinating gift from the deep sea.

Synthesis of six-membered oxygenated heterocycles through carbon-oxygen bond-forming reactions

Recent Developments in the Ferrier Rearrangement

This review is the third update of the original review, published in 1999, on the application of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings the topic to the end of 2004. Both fundamental studies and applications are covered. The main topics include methodological developments, matrices, fragmentation of carbohydrates and applications to large polymeric carbohydrates from plants, glycans from glycoproteins and those from various glycolipids. Other topics include the use of MALDI MS to study enzymes related to carbohydrate biosynthesis and degradation, its use in industrial processes, particularly biopharmaceuticals and its use to monitor products of chemical synthesis where glycodendrimers and carbohydrate-protein complexes are highlighted.

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Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004

Stereoselective synthesis of the lituarine tricyclic spiroacetal.

Stereoselective entry to beta-linked C-disaccharides using a carbon-Ferrier reaction.

11 – The Synthesis of C-linked Glycosides

The two-step synthesis of 4,6-O-benzylidene glucal, in 59% overall yield, from phenyl 1-seleno-α- d -mannopyranoside is described.

A new entry to 4,6-O-benzylidene glucal from phenyl 1-seleno-α-D-mannopyranoside

Oxidative cyclizations of 2-(4-hydroxybutyl)furan derivatives provide spirobutenolide acetals directly; on the basis of this methodology, we describe an asymmetric synthesis of a tricyclic spirobutenolide precursor to the C(7−18) fragment common to lituarines A−C.

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Paul Meo

Papers

Stereoselective synthesis of the lituarine tricyclic spiroacetal.

Stereoselective entry to beta-linked C-disaccharides using a carbon-Ferrier reaction.

11 – The Synthesis of C-linked Glycosides

A new entry to 4,6-O-benzylidene glucal from phenyl 1-seleno-α-D-mannopyranoside

Stereoselective Synthesis of the Lituarine Tricyclic Spiroacetal.