Showing papers in "Organic Letters in 2003"

TL;DR: Ligand-free Pd(OAc)(2) can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %.

TL;DR: A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant.

TL;DR: Silver iodide catalyzed the three-component coupling of aldehyde, alkyne, and amines to generate propargylic amines with high efficiency in water with no additional cocatalyst or activator required.

TL;DR: Ullmann-type diaryl ether synthesis can be performed at 90 degrees C using either aryl iodides or aryL bromides as the substrates under the assistance of N,N-dimethylglycine.

TL;DR: Preliminary results show that this reaction can be carried out under solvent-free conditions with comparable yields and a variety of functional groups are compatible with these reaction conditions.

TL;DR: A general and efficient copper-catalyzed method for the amidation of vinyl bromides and iodides has been developed and the double bond geometry of the vinyl halides was retained under the reaction conditions.

TL;DR: Ullmann-type aryl amination of aries iodides and aries bromides in DMSO gave the corresponding N-arylamines or N,N-diarylamines in good to excellent yields by using either N-methylglycine or L-proline as the ligand.

TL;DR: The construction of multivalent neoglycoconjugates is efficiently achieved by the regiospecific catalytic cycloaddition of alkynes and azides using the organic-soluble copper complexes (Ph(3)P)(3).CuBr and (EtO)( 3)P.

TL;DR: Free radicals generated by decomposition of benzoyl peroxide in the presence of alkyl iodides have been used to derivatize small-diameter single-wall carbon nanotubes (HiPco tubes) and exhibits remarkably improved solubility in organic solvents.

TL;DR: Highly stable NH salicylideneanilines have been prepared by reaction of 1,3,5-triformylphloroglucinol with aniline derivatives by X-ray crystallographic data and NMR studies.

TL;DR: It is reported that RuCl(3)/AgOTf has proven to be a hydroarylation catalyst with an efficiency and scope superior to previously known methods, providing good to excellent yields of cyclization products.

TL;DR: The structure of a palladacycle dimers possessing bridging halides using N-heterocyclic carbenes to generate novel monomeric complexes found to be equally active in aryl amination and alpha-arylation of ketones even at very low catalyst loading.

TL;DR: A general method for the coupling of aryl and vinyl halides with diaryl and dialkyl phosphines, as well as with dibutyl phosphite, is reported.

TL;DR: A new palladium-dipyridylmethylamine complex is an excellent catalyst for C-C bond-forming processes such as the Heck, Suzuki, and Sonogashira reactions in organic and aqueous solvents under homogeneous conditions.

TL;DR: Addition of aniline derivatives to aromatic and aliphatic alkynes proceeds efficiently in the presence of a gold(I) catalyst to afford ketimines in good yields.

TL;DR: A mild, efficient, high-yielding single-step variant of the Friedländer synthesis of quinolines, which employs SnCl( 2) and ZnCl(2) to effect the reaction.

TL;DR: A mild and general protocol for the copper-free Sonogashira coupling of aryl bromides with acetylenes has been developed and provides the active Pd(0) catalyst that allows subsequent coupling of various alkynes at room temperature with good to excellent yields.

TL;DR: Comparative control experiments suggest that the homocoupling yield is determined by concentration of both catalyst and oxygen.

TL;DR: A substantially red-shifted fluorescence emission in 3-hydroxyl-2-naphthanilide in acetonitrile was developed and drastically enhanced upon addition of anions such as F(-), AcO(-), and H(2)PO(4)(-), with the enhancement depending on anion basicity.

TL;DR: An N-heterocyclic carbene copper chloride (NHC−CuCl) complex has been prepared and used to catalyze the conjugate reduction of α,β-unsaturated carbonyl compounds.

TL;DR: The microwave-mediated three-component reaction of acyl bromide, pyridine, and acetylene is catalyzed by basic alumina to give corresponding indolizines in excellent yields in a one-pot reaction.

TL;DR: An efficient method for the synthesis of functionalized rhodamine derivatives has been developed that can be prepared from inexpensive precursors and purified without the use of chromatography for multicolor applications.

TL;DR: 2-Arylbenzoxazoles were directly synthesized from substituted 2-aminophenols and aldehydes in the presence of activated carbon (Darco KB) in xylene under an oxygen atmosphere.

TL;DR: The regioselective palladium(0)-catalyzed arylation of 3-furoate and 3-thiophenecarboxylate esters with aryl bromides with conditions that allow for the selective synthesis of either 2-aryl or 5-aryl products.

TL;DR: In this article, the regio-, stereo-, and enanti-lective direct addition of alpha-hydroxyketones to N-iPr-2,2'-bipyrrolidine is described.

TL;DR: A ligandless and base-free Cu-catalyzed protocol for the cross-coupling of arylboronic acids and potassium aryLtrifluoroborate salts with primary and secondary aliphatic amines and anilines is described.

TL;DR: This mild ynone synthesis is a suitable entry to 2,4-disubstituted pyrimidines in the sense of a one-pot three-component reaction, i.e., a coupling-addition-cyclocondensation sequence.

TL;DR: An easily accessible water-soluble chiral o-sulfonated 1,2-diphenylethlenediamine 2 and its mono-N-tosylated derivative 3 were synthesized for the first time.

TL;DR: A practical, one-pot, two-step catalytic method is described for the synthesis of 2,5-diformylfuran (DFF) from fructose via dehydration to 5-(hydroxymethyl)furfural (HMF), followed by in situ catalytic air-oxidation.

TL;DR: Air- and moisture-stable potassium alkenyl- and aryltrifluoroborate salts undergo cross-coupling with a variety of aliphatic primary and secondary alcohols and phenols, and are tolerant of a range of functional groups.