P
Paul W. Czoty
Researcher at Wake Forest University
Publications - 93
Citations - 2808
Paul W. Czoty is an academic researcher from Wake Forest University. The author has contributed to research in topics: Agonist & Self-administration. The author has an hindex of 28, co-authored 85 publications receiving 2426 citations. Previous affiliations of Paul W. Czoty include Emory University & Harvard University.
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Journal ArticleDOI
Why primate models matter
Kimberley A. Phillips,Karen L. Bales,Karen L. Bales,John P. Capitanio,John P. Capitanio,Alan J Conley,Paul W. Czoty,Bert A. 't Hart,William D. Hopkins,William D. Hopkins,Shiu Lok Hu,Lisa A. Miller,Lisa A. Miller,Michael A. Nader,Peter W. Nathanielsz,Jeffrey Rogers,Jeffrey Rogers,Carol A. Shively,Mary Lou Voytko +18 more
TL;DR: Key areas in biomedicine where primate models have been, and continue to be, essential for advancing fundamental knowledge in biomedical and biological research are reviewed.
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Pet imaging of dopamine D2 receptors in monkey models of cocaine abuse : Genetic predisposition versus environmental modulation
Michael A. Nader,Paul W. Czoty +1 more
TL;DR: There appears to be an inverse relationship between D2 receptor availability and vulnerability to the reinforcing effects of cocaine, and the development of novel animal models will extend understanding of the neurobiological basis of drug addiction to include a greater appreciation of the role of environmental factors.
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Evaluation of the “Pipeline” for Development of Medications for Cocaine Use Disorder: A Review of Translational Preclinical, Human Laboratory, and Clinical Trial Research
TL;DR: There was good concordance between animal and human laboratory results when the former assessed chronic drug treatment, and several subject-related, procedural, and environmental factors that differ between the laboratory and clinical trial settings that help explain the disagreement for other drugs were revealed.
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Serotonergic Attenuation of the Reinforcing and Neurochemical Effects of Cocaine in Squirrel Monkeys
TL;DR: The results obtained suggest that increasing brain 5-HT activity can attenuate the reinforcing effects of cocaine, ostensibly by decreasing the ability of cocaine to elevate extracellular DA in brain areas that mediate the behavioral effects.
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Relationship Between Social Rank and Cortisol and Testosterone Concentrations in Male Cynomolgus Monkeys (Macaca fascicularis)
TL;DR: Results indicate that basal cortisol and testosterone concentrations and HPA axis function are state variables that differentially reflect position in the dominance hierarchy, rather than trait variables that predict future social status.