P
Paul W. Ladenson
Researcher at Johns Hopkins University
Publications - 130
Citations - 15583
Paul W. Ladenson is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Thyroid & Thyroid cancer. The author has an hindex of 57, co-authored 128 publications receiving 14700 citations. Previous affiliations of Paul W. Ladenson include Johns Hopkins University School of Medicine & University of Miami.
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Journal ArticleDOI
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
Mingzhao Xing,William H. Westra,Ralph P. Tufano,Yoram Cohen,Eli Rosenbaum,Kerry J. Rhoden,Kathryn A. Carson,Vasily Vasko,A Larin,Giovanni Tallini,Sara M. Tolaney,Elizabeth H. Holt,Pei Hui,Christopher B. Umbricht,Shehzad Basaria,Marge Ewertz,Anthony P. Tufaro,Joseph A. Califano,Matthew D. Ringel,Martha A. Zeiger,David Sidransky,Paul W. Ladenson +21 more
TL;DR: In patients with PTC, BRAF mutation is associated with poorer clinicopathological outcomes and independently predicts recurrence, and may be a useful molecular marker to assist in risk stratification for patients withPTC.
Journal ArticleDOI
BRAF Mutation in Papillary Thyroid Carcinoma
Yoram Cohen,Mingzhao Xing,Elizabeth Mambo,Zhongmin Guo,Guogun Wu,Barry Trink,Uziel Beller,William H. Westra,Paul W. Ladenson,David Sidransky +9 more
TL;DR: The data suggest that activating BRAF mutations may be an important event in the development of papillary thyroid cancer.
Journal ArticleDOI
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
Michael Mingzhao Xing,Ali S. Alzahrani,Kathryn A. Carson,David Viola,Rossella Elisei,Bela Bendlova,Linwah Yip,Caterina Mian,Federica Vianello,R. Michael Tuttle,Eyal Robenshtok,James A. Fagin,Efisio Puxeddu,Laura Fugazzola,Agnieszka Czarniecka,Barbara Jarzab,Christine J. O'Neill,Mark Sywak,Alfred King-Yin Lam,Garcilaso Riesco-Eizaguirre,Garcilaso Riesco-Eizaguirre,Pilar Santisteban,Hirotaka Nakayama,Ralph P. Tufano,Sara I. Pai,Martha A. Zeiger,William H. Westra,Douglas P. Clark,Roderick J. Clifton-Bligh,David Sidransky,Paul W. Ladenson,Vlasta Sykorova +31 more
TL;DR: In this retrospective multicenter study, the presence of the BRAF V600E mutation was significantly associated with increased cancer-related mortality among patients with PTC, and the association was not independent of tumor features.
Journal ArticleDOI
Thyroid status, cardiovascular risk, and mortality in older adults
Anne R. Cappola,Linda P. Fried,Alice M. Arnold,Mark D. Danese,Lewis H. Kuller,Gregory L. Burke,Russell P. Tracy,Paul W. Ladenson +7 more
TL;DR: The data show an association between subclinical hyperthyroidism and development of atrial fibrillation but do not support the hypothesis that unrecognized subclinical hypothyroidism or subclinical Hypothyroidistan is associated with other cardiovascular disorders or mortality.
Journal ArticleDOI
A consensus report of the role of serum thyroglobulin as a monitoring method for low-risk patients with papillary thyroid carcinoma.
Ernest L. Mazzaferri,Richard J. Robbins,Carole A. Spencer,Lewis E. Braverman,Furio Pacini,Leonard Wartofsky,Bryan R. Haugen,Steven I. Sherman,David S. Cooper,Glenn D. Braunstein,Stephanie L. Lee,Terry F. Davies,Baha'uddin M. Arafah,Paul W. Ladenson,Aldo Pinchera +14 more
TL;DR: A surveillance guideline is proposed using TSH-stimulated Tg levels for patients who have undergone total or near-total thyroidectomy and (131)I ablation for DTC and have no clinical evidence of residual tumor with a serum Tg below 1 micro g/liter during THST.