Paulus Kristanto

TL;DR: Characteristics of dosing history in patients prescribed a once a day antihypertensive medication are described, finding that early discontinuation of treatment and suboptimal daily execution of the prescribed regimens are the most common facets of poor adherence with once aDay anti Hypertensive drug treatments.

TL;DR: Notwithstanding the statistical heterogeneity among the studies identified, and potential publication bias, the evidence from the meta-analysis suggests that EM-feedback and cognitive-educational interventions are potentially effective approaches to enhance patient adherence to medications.

TL;DR: Regimen implementation of tacrolimus once daily is significantly superior to the twice-daily regimen and there was a residual prevalence of suboptimal adherence that will have to be countered by means other than reformulation and regimen simplification.

TL;DR: This randomized controlled trial enrolled adult heart, liver, and lung transplant recipients who were >1 year post-transplant and on tacrolimus twice daily and was efficacious in improving adherence and sustainable.

TL;DR: Adherence, even in the early stages of treatment, appears to be insufficient in some patients and may be below the level required for continuous inhibition of viral replication, which may lead to improved targeting of counselling about their medication intake of patients in order to prevent occurrence of resistant viral strains.