Pedro Bullón

TL;DR: Current evidence for oxidative damage in chronic inflammatory periodontal disease, and the possible therapeutic effects of anti-oxidants in treating and/or preventing such pathology, are reviewed, with special attention to vitamin E and Co-enzyme Q.

TL;DR: The antioxidant capacity of saliva could constitute a first line of defence against free radical-mediated oxidative stress, since the process of mastication and digestion of ingested foods promotes a variety of reactions, including lipid peroxidation.

TL;DR: Oxidative stress may act as a potential common link to explain relationships between each component of metabolic syndrome and periodontitis, with increased serum levels of products derived from oxidative damage.

TL;DR: The aim of this review was to consider and discuss the mounting evidence that the basis for the inter-relationships between chronic periodontitis and atheromatous disease and diabetes lie at a fundamental intracellular level, namely oxidative stress and mitochondrial dysfunction, as a meeting background among such chronic diseases andperiodontitis.

TL;DR: The data have shown that antidepressant‐mediated autophagy may have a role in restoration of certain metabolic and immunological pathways in MDD patients, and therefore the monitoring of NLRP3 expression levels and/or IL‐1&bgr;/IL‐18 release may have clinical value in drug selection.