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José Antonio Sánchez-Alcázar

Researcher at Spanish National Research Council

Publications -  114
Citations -  15130

José Antonio Sánchez-Alcázar is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Mitochondrion & Coenzyme Q10. The author has an hindex of 39, co-authored 105 publications receiving 12142 citations. Previous affiliations of José Antonio Sánchez-Alcázar include Complutense University of Madrid & New York State Department of Health.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder.

Elísabet Alcocer-Gómez, +6 more
- 01 Feb 2014 - 
TL;DR: The role of NLRP3 inflammasome complex in the maturation of caspase-1 and the processing of its substrates, IL-1β and IL-18, in blood cells from MDD patients is investigated to provide new insight into the pathogenic mechanism of MDD.
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Coenzyme Q deficiency triggers mitochondria degradation by mitophagy.

Ángeles Rodríguez-Hernández, +9 more
- 01 Jan 2009 - 
TL;DR: Assays of cultured fibroblasts revealed decreased activities of complex II+III, complex III, and complex IV, reduced expression of mitochondrial proteins involved in oxidative phosphorylation, decreased mitochondrial membrane potential, increased production of reactive oxygen species (ROS), activation of mitochondrial permeability transition (MPT), and reduced growth rates which were partially restored by CoQ supplementation.