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Pedro Eduardo Fröehlich
Researcher at Universidade Federal do Rio Grande do Sul
Publications - 80
Citations - 1041
Pedro Eduardo Fröehlich is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Dissolution testing & Pharmacokinetics. The author has an hindex of 18, co-authored 80 publications receiving 924 citations.
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Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass.
TL;DR: A pilot study to verify if the usual dose adjustment based on body surface area (BSA) would be producing the same plasma concentration-time profiles in patients with normal (<25) and above normal (>25) body mass index (BMI).
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Determination of amphetamine-type stimulants in oral fluid by solid-phase microextraction and gas chromatography–mass spectrometry
Daniele Zago Souza,Daniele Zago Souza,Paula Otero Boehl,Eloisa Comiran,Kristiane de Cássia Mariotti,Flavio Pechansky,Paulina do Carmo Arruda Vieira Duarte,Raquel Brandini De Boni,Pedro Eduardo Fröehlich,Renata Pereira Limberger +9 more
TL;DR: The validated method can be easily automated and then used for screening and confirmation of amphetamine-type stimulants in drivers' oral fluid and the goodness-of-fit concerning the ordinary least squares model in the statistical inference of data has been tested through residual plotting and ANOVA.
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Development and validation of dissolution test for ritonavir soft gelatin capsules based on in vivo data
Rochele Cassanta Rossi,Carolina Lupi Dias,Eliane Maria Donato,Laura Alegria Martins,Ana Maria Bergold,Pedro Eduardo Fröehlich +5 more
TL;DR: Both the HPLC method and the dissolution test are validated and could be used to evaluate the dissolution profile of ritonavir soft gelatin capsules.
Journal ArticleDOI
LC Method for Studies on the Stability of Lopinavir and Ritonavir in Soft Gelatin Capsules
Eliane Maria Donato,Carolina Lupi Dias,Rochele Cassanta Rossi,R. S. Valente,Pedro Eduardo Fröehlich,Ana Maria Bergold +5 more
TL;DR: In this article, a stability-indicating HPLC method was proposed to quantify ritonavir (RTV) and lopinavir (LPV) in soft gelatin capsules.
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High prevalence of hypovitaminosis D and secondary hyperparathyroidism in elders living in nonprofit homes in South Brazil.
TL;DR: Hypovitaminosis D and secondary hyperparathyroidism (SHP) are highly prevalent in elders living in old-age homes; however, SHP was independently related with age, 25(OH)D, GFR, and hydrochlorothiazide use.