P
Pedro L. Oliveira
Researcher at Federal University of Rio de Janeiro
Publications - 122
Citations - 6398
Pedro L. Oliveira is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Rhodnius prolixus & Heme. The author has an hindex of 44, co-authored 112 publications receiving 5565 citations. Previous affiliations of Pedro L. Oliveira include Johns Hopkins University.
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Journal ArticleDOI
Mitochondrial Reactive Oxygen Species Modulate Mosquito Susceptibility to Plasmodium Infection
Renata L.S. Goncalves,Renata L.S. Goncalves,Jose Henrique M. Oliveira,Jose Henrique M. Oliveira,Giselle de Almeida Oliveira,John F. Andersen,Marcus F. Oliveira,Pedro L. Oliveira,Carolina Barillas-Mury +8 more
TL;DR: Direct experimental evidence is provided indicating that ROS derived from mitochondria can modulate mosquito epithelial responses to Plasmodium infection.
Journal ArticleDOI
Blood-feeding induces reversible functional changes in flight muscle mitochondria of Aedes aegypti mosquito.
Renata L.S. Goncalves,Ana Carolina Loyola Machado,Gabriela O. Paiva-Silva,Marcos Henrique Ferreira Sorgine,Marisa M. Momoli,Jose Henrique M. Oliveira,Marcos A. Vannier-Santos,Antonio Galina,Pedro L. Oliveira,Marcus F. Oliveira +9 more
TL;DR: The effects of blood-feeding on flight muscle (FM) mitochondria from the mosquito Aedes aegypti, a vector of dengue and yellow fever, are investigated, finding that mitochondria fuse upon blood meal, a condition related to reduced ROS generation.
Journal ArticleDOI
Antioxidant pathways are up-regulated during biological nitrogen fixation to prevent ROS-induced nitrogenase inhibition in Gluconacetobacter diazotrophicus
Sylvia Maria Campbell Alquéres,Jose Henrique M. Oliveira,Eduardo de Matos Nogueira,H. V. Guedes,Pedro L. Oliveira,Fernando Portela Câmara,José Ivo Baldani,Orlando B. Martins +7 more
TL;DR: It is suggested that careful controlled ROS production during this critical phase is an adaptive mechanism to allow nitrogen fixation and altered redox metabolism during BNF by increasing antioxidant transcript levels resulting in a lower ROS generation.
Journal ArticleDOI
Ovarian dual oxidase (Duox) activity is essential for insect eggshell hardening and waterproofing
Felipe A. Dias,Ana Caroline P. Gandara,Fernanda G. Queiroz-Barros,Raquel L.L. Oliveira,Marcos Henrique Ferreira Sorgine,Glória R.C. Braz,Pedro L. Oliveira +6 more
TL;DR: Working with Rhodnius prolixus, the insect vector of Chagas disease, it is shown that an ovary dual oxidase (Duox), a NADPH oxidase, is the source of the H2O2 that supports dityrosine-mediated protein cross-linking and eggshell hardening.
Journal ArticleDOI
Biglutaminyl-biliverdin IX alpha as a heme degradation product in the dengue fever insect-vector Aedes aegypti.
TL;DR: Structural characterization by ESI-MS revealed that the mosquito pigment is the alpha isomer of biliverdin bound to two glutamine residues by an amide bond, and its mobility on a reverse-phase chromatography column suggested a compound less hydrophobic than biliverin IXalpha.