P
Pedro L. Oliveira
Researcher at Federal University of Rio de Janeiro
Publications - 122
Citations - 6398
Pedro L. Oliveira is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Rhodnius prolixus & Heme. The author has an hindex of 44, co-authored 112 publications receiving 5565 citations. Previous affiliations of Pedro L. Oliveira include Johns Hopkins University.
Papers
More filters
Journal ArticleDOI
Inhibition of heme aggregation by chloroquine reduces Schistosoma mansoni infection.
Marcus F. Oliveira,Joana C. D’Avila,Antônio J Tempone,Juliana B. R. Correâ Soares,Franklin David Rumjanek,Antonio Ferreira-Pereira,Sergio T. Ferreira,Pedro L. Oliveira +7 more
TL;DR: Results indicate that inhibition of formation of Hz in S. mansoni, by CLQ, led to an important decrease in the overall severity of experimental murine schistosomiasis, and suggest that formation ofHz is a major mechanism of heme detoxification and a potential target for chemotherapy in the parasite.
Journal ArticleDOI
Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes.
Flávio Alves Lara,Celso Sant’Anna,D. Lemos,G.A.T. Laranja,Marsen Garcia Pinto Coelho,I. Reis Salles,A. Michel,Pedro L. Oliveira,Narcisa L. Cunha-e-Silva,Didier Salmon,Marcia Cristina Paes +10 more
TL;DR: It is concluded that a P-glycoprotein homologue transporter is probably involved in heme transport through the plasma membrane because heme internalization proceeded much faster than that observed by hemoglobin-rhodamine.
Journal ArticleDOI
Microbiota activates IMD pathway and limits Sindbis infection in Aedes aegypti.
Ana Beatriz F. Barletta,Maria Clara L. Nascimento-Silva,Octavio A. C. Talyuli,Jose Henrique M. Oliveira,Luiza de Oliveira Ramos Pereira,Pedro L. Oliveira,Marcos Henrique Ferreira Sorgine +6 more
TL;DR: It is suggested that a blood meal is able to activate innate immune pathways, through a nutrient induced growth of microbiota, leading to upregulation of aaREL2 and IMD activation, and SINV replication in Ae.
Journal ArticleDOI
Lipophorin and oögenesis in Rhodnius prolixus: Transfer of phospholipids
TL;DR: The lipophorin of Rhodnius prolixus was metabolically labelled with 32P exclusively in the phospholipid moiety and purified on a potassium bromide gradient and the kinetics of incorporation were linear and the process was impaired at low temperature.
Journal ArticleDOI
Multi-antigenic vaccine against the cattle tick Rhipicephalus (Boophilus) microplus: a field evaluation.
Luís Fernando Parizi,José Reck,Daiane Patrícia Oldiges,Melina Garcia Guizzo,Adriana Seixas,Adriana Seixas,Carlos Logullo,Pedro L. Oliveira,Carlos Termignoni,João Ricardo Martins,Itabajara da Silva Vaz +10 more
TL;DR: A three-antigen vaccine was composed by three tick recombinant proteins from two tick species that in previous single-vaccination reports provided partial protection of confined cattle against R. microplus infestations, and increased antibody levels against three proteins were recorded after immunizations.