Peiwei Chai

TL;DR: It is clarified that the abnormal changes in the m6A enrichment of specific loci contribute to tumour occurrence and development, thereby representing a novel anti-cancer strategy by restoration to balanced RNA methylation in tumour cells.

TL;DR: In this paper, the role of histone lactylation in tumorigenesis remains unclear, but it is shown that histone Lactylation is elevated in tumors and is associated with poor prognosis of ocular melanoma.

TL;DR: An autophagy regulation strategy is reported by emancipating target‐functionalized carbon dots from autophagic vesicles for the efficient visualized tumor therapy by achieving therapeutic effects with high performance in 26 types of tumor cell lines.

TL;DR: It is shown that RNA methylation significantly inhibits the progression of UM and CM, and uncovers a critical function for m6A methylation in ocular melanoma and provides additional insight into the understanding of m 6A modification.

TL;DR: This study for the first time curated both genetic and epigenetic variations of ACE2 in human malignancies in human cancers, and because this study is a bioinformatics assay, further functional and clinical validation is warranted.