Peng Chen

TL;DR: A three-dimensional nanostructured microfluidic chip is presented, in which arrays of micropillars were functionalized with crisscrossed multiwall carbon nanotubes by chemical deposition, to capture exosomes with high efficiency through a combination of a specific recognition molecule (CD63) and the unique topography of the nanomaterials.

TL;DR: The designer exosome combines the merits of both synthetic materials and the natural nanovesicles and gains multiple abilities for efficient tumor targeting, controlled release, and thermal therapy like synthetic nanocarriers.

TL;DR: The development of metal cation monitoring technology that uses ultrasmall nanoclusters as the sensing probes and a fresh opinion on research expectations in the field of inorganic nanoscience and nanotechnology are provided.

TL;DR: This work integrated the three functions in one electrochemical microchip by intentionally designing a cactus-like, topologically structured conductive array consisted of a PDMS micropillar-array core and an electroconductive gold coating layer with hierarchical structure that presented a capture efficiency of 85-100% and promised a significant application in the clinical field.

TL;DR: The results confirmed that the multifunctional gradients-customizing microfluidic devices were a highly efficient way to analyze multidrug resistance (MDR) at single-cell or even single-organelle level with advantages of high-throughput, flexibility, stability and low sample consumption.