Xiaojun Feng

TL;DR: A three-dimensional nanostructured microfluidic chip is presented, in which arrays of micropillars were functionalized with crisscrossed multiwall carbon nanotubes by chemical deposition, to capture exosomes with high efficiency through a combination of a specific recognition molecule (CD63) and the unique topography of the nanomaterials.

TL;DR: The designer exosome combines the merits of both synthetic materials and the natural nanovesicles and gains multiple abilities for efficient tumor targeting, controlled release, and thermal therapy like synthetic nanocarriers.

TL;DR: The advances of Chip-MS in the past decade are reviewed, covering innovations in microchip fabrication, microchips coupled to electrospray ionization (ESI)-MS and matrix-assisted laser desorption/ionization (MALDI)-MS.

TL;DR: The engineered exosomes represent a potential new therapeutic tool for angiogenesis therapy and imaging in a bio-friendly manner and are pioneered biomimetic particles with topographic structures for exosome isolation.

TL;DR: Heterogeneous 3D cell microenvironment arrays are rapidly assembled by combining surface-wettability-guided assembly and microdroplet-array-based operations, which provides a cost-effective solution to meet the increasing demand of stem cell research, tissue engineering, and drug screening.