Pengrui Wang

TL;DR: 3D hydrogel-based triculture model that embeds hiPSC-HPCs with human umbilical vein endothelial cells and adipose-derived stem cells in a microscale hexagonal architecture is presented and finds improved morphological organization, higher liver-specific gene expression levels, increased metabolic product secretion, and enhanced cytochrome P450 induction.

TL;DR: This work created prevascularized tissues with complex three-dimensional (3D) microarchitectures using a rapid biop printing method - microscale continuous optical bioprinting (μCOB) that can be broadly applicable to the engineering and translation of various functional tissues.

TL;DR: The development of biomaterials suited for light-based 3D printing modalities with an emphasis on bioprinting applications are reviewed and the chemical mechanisms that govern photopolymerization are discussed.

TL;DR: A rapid light-based 3D bioprinting process and an engineered cancer tissue platform possessing tissue-scale organization and distinct regional stiffness enabled the visualization of HepG2 stromal invasion from the nodule with cirrhotic stiffness.

TL;DR: This work described a method to produce photocrosslinkable tissue-specific dECM bioinks for fabricating patient-specific tissues with high control over complex microarchitecture and mechanical properties using a digital light processing (DLP)-based scanningless and continuous 3D bioprinter.