W
Wenhao Chen
Researcher at Houston Methodist Hospital
Publications - 91
Citations - 2784
Wenhao Chen is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: T cell & Transplantation. The author has an hindex of 24, co-authored 78 publications receiving 2420 citations. Previous affiliations of Wenhao Chen include University Health Network & University of Toledo.
Papers
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Journal ArticleDOI
Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
Christophe Depre,Gregory L. Shipley,Wenhao Chen,Qiuying Han,Torsten Doenst,Meredith L. Moore,Stanislaw M. Stepkowski,Peter J.A. Davies,Heinrich Taegtmeyer +8 more
TL;DR: In this article, the authors compared the patterns of gene expression in unloaded rat heart with those in hypertrophied rat heart and found that both conditions induced a re-expression of growth factors and proto-oncogenes, and a downregulation of the adult isoforms, but not of the 'fetal' isoforms.
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Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer
TL;DR: A set of key cytokines secreted by ovarian tumor cells and tumor-associated APCs that favor the generation and expansion of human Th17 cells are identified and should accelerate efforts to define the function of this important subset of CD4+ T cells in the human immune response to cancer.
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Characterization of Distinct Conventional and Plasmacytoid Dendritic Cell-Committed Precursors in Murine Bone Marrow
TL;DR: It is reported that murine CD11c+MHC II− bone marrow cells, which are immediate DC precursors of CD8 α+, CD8α−, and B220+ DC in vivo, can be separated into B 220+ and B 220− DC precursor subpopulations.
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In Situ Replication of Immediate Dendritic Cell (DC) Precursors Contributes to Conventional DC Homeostasis in Lymphoid Tissue
Jun Diao,Erin Winter,Claude Cantin,Wenhao Chen,Luoling Xu,David J. Kelvin,Jim Phillips,Jim Phillips,Mark S. Cattral +8 more
TL;DR: It is shown that mouse CD11c+ MHC class II−lineage− cells are immediate precursors of conventional DC and are widely distributed in both bone marrow and lymphoid tissues and highlight the importance of in situ replication of immediate DCp and DC in maintaining conventional DC populations.
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“Default” Generation of Neonatal Regulatory T Cells
Guohua Wang,Yoshihiro Miyahara,Zhiyong Guo,Zhiyong Guo,Mithun Khattar,Stanislaw M. Stepkowski,Wenhao Chen +6 more
TL;DR: In this paper, the induction of Treg cells from neonatal T cells with various TCR stimulatory conditions, because TCR stimulation is required for Treg cell generation, was studied.