Simulated gastro-intestinal digestion is widely employed in many fields of food and nutritional sciences, as conducting human trials are often costly, resource intensive, and ethically disputable. As a consequence, in vitro alternatives that determine endpoints such as the bioaccessibility of nutrients and non-nutrients or the digestibility of macronutrients (e.g. lipids, proteins and carbohydrates) are used for screening and building new hypotheses. Various digestion models have been proposed, often impeding the possibility to compare results across research teams. For example, a large variety of enzymes from different sources such as of porcine, rabbit or human origin have been used, differing in their activity and characterization. Differences in pH, mineral type, ionic strength and digestion time, which alter enzyme activity and other phenomena, may also considerably alter results. Other parameters such as the presence of phospholipids, individual enzymes such as gastric lipase and digestive emulsifiers vs. their mixtures (e.g. pancreatin and bile salts), and the ratio of food bolus to digestive fluids, have also been discussed at length. In the present consensus paper, within the COST Infogest network, we propose a general standardised and practical static digestion method based on physiologically relevant conditions that can be applied for various endpoints, which may be amended to accommodate further specific requirements. A frameset of parameters including the oral, gastric and small intestinal digestion are outlined and their relevance discussed in relation to available in vivo data and enzymes. This consensus paper will give a detailed protocol and a line-by-line, guidance, recommendations and justifications but also limitation of the proposed model. This harmonised static, in vitro digestion method for food should aid the production of more comparable data in the future.

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A standardised static in vitro digestion method suitable for food – an international consensus

A positive temperature coefficient is the term which has been used to indicate that an increase in solubility occurs as the temperature is raised, whereas a negative coefficient indicates a decrease in solubility with rise in temperature.

Effect of Temperature

Nanoemulsions fabricated from food-grade ingredients are being increasingly utilized in the food industry to encapsulate, protect, and deliver lipophilic functional components, such as biologically-active lipids (e.g., ω-3 fatty acids, conjugated linoleic acid) and oil-soluble flavors, vitamins, preservatives, and nutraceuticals. The small size of the particles in nanoemulsions (r<100 nm) means that they have a number of potential advantages over conventional emulsions-higher stability to droplet aggregation and gravitational separation, high optical clarity, ability to modulate product texture, and, increased bioavailability of lipophilic components. On the other hand, there may also be some risks associated with the oral ingestion of nanoemulsions, such as their ability to change the biological fate of bioactive components within the gastrointestinal tract and the potential toxicity of some of the components used in their fabrication. This review article provides an overview of the current status of nanoemulsion formulation, fabrication, properties, applications, biological fate, and potential toxicity with emphasis on systems suitable for utilization within the food and beverage industry.

Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity.

http://ssu.ac.ir/cms/fileadmin/user_upload/Mtahghighat/tfood/ARTICLES/microb-safety/Significance_of_microbial_biofilms_in_food_industry_a_review.pdf

Significance of microbial biofilms in food industry: a review

Foresight. Tackling obesities: future choices. Project report.

Engineering and chemical factors associated with fouling and cleaning in milk processing

Summary
Ohmic heating is a food processing operation in which heat is internally generated within foods by the passage of alternating electric current. The process enables solid particles to heat as fast as liquids, thus making it possible to use High Temperature Short Time sterilization techniques on particulate foods. Ohmic heating rates are critically dependent on the electrical conductivities of the foods being processed, about which little information is available. This paper reports experiments to determine the changes in electrical conductivity which occur during ohmic heating of some common foods. A number of effects which occur during conventional heating, such as starch transition, melting of fats and cell structure changes, are shown to affect the electrical conductivity. In some cases the presence of an electric field induces enhanced diffusion of cell fluids in the food which increases the rate of change of conductivity with temperature above that found by conventional heating. Preheating is found to increase the electrical conductivity of some foods, making them acceptable for ohmic processing.

Changes in the electrical conductivity of foods during ohmic heating

Cleaning of process plant is ubiquitous in the food industry but is still poorly understood. Fouling research has benefitted from the use of a simplified classification of mechanisms. Here we review current work in food and personal product cleaning, and propose two classifications for cleaning problems, one based on soil type and one based on cleaning mechanism. The aim of the classification is both to allow results from different cleaning problems to be compared and to aid in the development of solutions that are effective across the industry.

Peter J. Fryer

Papers

Engineering and chemical factors associated with fouling and cleaning in milk processing

Changes in the electrical conductivity of foods during ohmic heating

A prototype cleaning map: A classification of industrial cleaning processes

Enhanced cleaning of whey protein soils using pulsed flows

The effect of Reynolds number and fluid temperature in whey protein fouling