Peter M. Tessier

TL;DR: In this article, a new class of metallic materials with long-range nano-scale ordering and hierarchical porosity was synthesized by using colloidal crystals as templates, and they were used to fabricate structures from inorganic oxides, polymers, diamond and glassy carbon.

TL;DR: Surprisingly, resveratrol does not remodel non-toxic oligomers or accelerate Aβ monomer aggregation despite that both conformers possess random coil secondary structures indistinguishable from soluble oligomers and significantly different from their β-sheet rich, fibrillar counterparts.

TL;DR: This work has measured protein interactions using self-interaction chromatography, in which protein is immobilized on chromatographic particles and the retention of the same protein is measured in isocratic elution, and obtains quantitative agreement between virial coefficients measured by self- INTERACTION chromatography and traditional characterization methods over a wide range of pH and ionic strengths.

TL;DR: The results suggest that the ability of non-fibrillar Aβ oligomers to interact with and disrupt cellular membranes is linked to the degree of solvent exposure of their central and C-terminal hydrophobic peptide segments.