Peter Schwartz

TL;DR: It is shown that Ambra1 (activating molecule in Beclin1-regulated autophagy), a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulatesAutophagy and has a crucial role in embryogenesis, and provides in vivo evidence supporting the existence of a complex interplay between autphagy, cell growth and cell death required for neural development in mammals.

TL;DR: Cardiac myocytes isolated from adult rats can be kept in culture with physiological calcium concentrations up to four days, and over this time cardiocytes preserve their normal ultrastructure.

TL;DR: The question whether enzyme release may already occur during reversible injury is of considerable relevance in clinical medicine because the amount of released enzyme activity has been used to estimate the mass of damaged tissue in cardiac infarction and because the stress of some diagnostic interventions may lead to cardiac enzyme release, which according to the irreversibility hypothesis would indicate the death of cells in a cell constant organ.

TL;DR: The results indicate that agents which stimulate protein kinase C (alpha 1-agonists, phorbol esters) stimulate cell spreading, protein synthesis and long-term survival of cardiomyocytes in vitro.

TL;DR: Two mitochondrial subpopulations were isolated from guinea-pig heart by density gradient centrifugation and found that changes develop most evidently at the very beginning of ischemia for NAD-linked respiration.