Peter van Vliet

TL;DR: Cognitive outcomes from the randomized placebo-controlled PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) are presented and it is concluded that Employing statin therapy in the elderly in an attempt to prevent cognitive decline seems to be futile.

TL;DR: The severity of disturbances in cerebral hemodynamics is significantly lower in Alzheimer's disease compared to vascular dementia and the effect sizes indicating the standardized mean differences of the hemodynamic measures between two groups were calculated.

TL;DR: Factors that influence cholesterol metabolism, such as dietary intake, are shown to play a role in late-life cognitive function and the risk of dementia, but the association is strongly age-dependent.

TL;DR: High total serum cholesterol in middle age is associated with cognitive impairment and statin therapy is likely to have a benefit on cognitive function via a decrease of cardiovascular pathologies, however, a beneficial effect of cholesterol lowering on Cognitive function in old age is uncertain.

TL;DR: In this paper, the authors examined whether the level of physical and cognitive function moderates the association between blood pressure and stroke in the oldest old, and they found that impaired cognitive functioning was associated with reduced risk of stroke.