M
Matthias J.P. van Osch
Researcher at Leiden University Medical Center
Publications - 236
Citations - 10936
Matthias J.P. van Osch is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Cerebral blood flow & Medicine. The author has an hindex of 50, co-authored 205 publications receiving 8963 citations. Previous affiliations of Matthias J.P. van Osch include Loyola University Medical Center & Leiden University.
Papers
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Journal ArticleDOI
Recommended Implementation of Arterial Spin Labeled Perfusion MRI for Clinical Applications: A consensus of the ISMRM Perfusion Study Group and the European Consortium for ASL in Dementia
David C. Alsop,John A. Detre,Xavier Golay,Matthias Günther,Jeroen Hendrikse,Luis Hernandez-Garcia,Hanzhang Lu,Bradley J. MacIntosh,Bradley J. MacIntosh,Laura M. Parkes,Marion Smits,Matthias J.P. van Osch,Danny J.J. Wang,Eric C. Wong,Greg Zaharchuk +14 more
TL;DR: This review provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications and describes the major considerations and trade‐offs in implementing an ASL protocol and provides specific recommendations for a standard approach.
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Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
Harm J. van de Haar,Saartje Burgmans,Jacobus F.A. Jansen,Matthias J.P. van Osch,Mark A. van Buchem,Majon Muller,Paul A. M. Hofman,Frans R.J. Verhey,Walter H. Backes +8 more
TL;DR: The results of this study showed global BBB leakage in patients with early AD that is associated with cognitive decline that may be part of a cascade of pathologic events that eventually lead to cognitive decline and dementia.
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Probabilistic segmentation of white matter lesions in MR imaging.
Petronella Anbeek,Koen L. Vincken,Matthias J.P. van Osch,Robertus H.C. Bisschops,Jeroen van der Grond +4 more
TL;DR: This method for automated WML segmentation reaches an accuracy that is comparable to methods for multiple sclerosis (MS) lesion segmentation and is suitable for detection of WMLs in large and longitudinal population studies.
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Assessment of middle cerebral artery diameter during hypocapnia and hypercapnia in humans using ultra-high-field MRI
Jasper Verbree,Anne-Sophie G. T. Bronzwaer,Eidrees Ghariq,Maarten J. Versluis,Mat J.A.P. Daemen,Mark A. van Buchem,Albert Dahan,Johannes J. van Lieshout,Johannes J. van Lieshout,Matthias J.P. van Osch +9 more
TL;DR: The MCA diameter remains constant during small deviations of the PET( CO2) from normocapnia, but increases at higher PET(CO2) values, while Cerebral blood flow changes measured by transcranial Doppler could be corrected by this calibration curve using concomitant PET(co2) measurements.
Journal ArticleDOI
Estimation of Labeling Efficiency in Pseudocontinuous Arterial Spin Labeling
Sina Aslan,Feng Xu,Peiying L. Wang,Jinsoo Uh,Uma S. Yezhuvath,Matthias J.P. van Osch,Hanzhang Lu +6 more
TL;DR: It is suggested that labeling efficiency is a critical parameter in pseudocontinuous arterial spin labeling MRI not only in terms of achieving highest sensitivity but also in quantification of absolute cerebral blood flow in milliliters per minute per 100 g.