P
Peter Youssef
Researcher at Royal Prince Alfred Hospital
Publications - 82
Citations - 3263
Peter Youssef is an academic researcher from Royal Prince Alfred Hospital. The author has contributed to research in topics: Rheumatoid arthritis & Synovial membrane. The author has an hindex of 25, co-authored 75 publications receiving 2874 citations. Previous affiliations of Peter Youssef include University of Sydney & University of New South Wales.
Papers
More filters
Journal Article
Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.
TL;DR: Chronic inflammatory changes with production of proinflammatory cytokines are a feature of synovial membranes from patients with early OA, with the most severe changes seen in patients at the time of joint replacement surgery resembling those seen in rheumatoid arthritis.
Journal ArticleDOI
Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial
Roy Fleischmann,Eduardo Mysler,Stephen Hall,Alan J Kivitz,Robert J. Moots,Zhen Luo,Ryan DeMasi,Koshika Soma,Richard Zhang,Liza Takiya,Svitlana Tatulych,Christopher F. Mojcik,Sriram Krishnaswami,Sujatha Menon,Josef S Smolen,Luthando Adams,Mahmood M Ally,Maria C du Plooy,Ingrid Louw,Savithree Nayiager,Christoffel B Nel,Debra Nel,Helmuth Reuter,Ahmed S Soloman,Catherine E Spargo,Maureen Rischmueller,Shunil D Sharma,Robert K Will,Peter Youssef,Caroline Arroyo,Rosario P Baes,Roger B Dulos,Llewellyn T Hao,Allan E Lanzon,Juan Javier T Lichauco,Jill H Mangubat,Edgar B Ramiterre,Bernadette Heizel M Reyes,Perry P Tan,Jung-Yoon Choe,Young Mo Kang,Seong Ryul Kwon,Sang-Heon Lee,Shin-Seok Lee,Dae-Hyun Yoo,Hsiao-Yi Lin,Shue-Fen Luo,Shih-Tzu Tsai,Wen-Chan Tsai,Jui-Cheng Tseng,Cheng-Chung C Wei,Paijit Asavatanabodee,Kanokrat Nantiruj,Surasak Nilganuwong,Parichat Uea-Areewongsa,Ljubinka Bozic Majstorovic,Suada Mulic Bacic,Anastas Batalov,Gabriela Georgieva-Slavcheva,Mariyana Mihailova,Nikolay G Nikolov,Dimitar P Penev,Yuliy A Spasov,Krasimira Stanimirova,Stoyan Todorov,Antoaneta R Toncheva,Nadezhda Yordanova,Zdenka Mosterova,Libor Novosad,Leona Prochazkova,Helena Stehlikova,Zuzana Stejfova,Natalia Kiseleva,Lea Pank,Triin Savi,Balbir-Gurman Alexandra,Howard Amital,Dror Mevorach,Itzhak A Rosner,Anna Mihailova,Evija Stumbra-Stumberga,Vida Basijokiene,Virginija Lietuvininkiene,Dalia Unikiene,Jan Brzezicki,Anna Dudek,Maria B Glowacka-Kulesz,Barbara Grabowicz-Wasko,Sabina Hajduk-Kubacka,Joanna Hilt,Pawel Hrycaj,Slawomir Jeka,Renata Kolasa,Marek Krogulec,Hanna Mastalerz,Anna Olak-Popko,Elzbieta Owczarek,Zofia Ruzga,Alina Walczak,Codrina I Ancuta,Ioan Ancuta,Andra R Balanescu,Florian Berghea,Silvia Bojin,Mihaela A Ianuli Arvunescu,Ruxandra M Ionescu,Eugenia Mociran,Mariana Pavel,Simona Rednic,Adriana Voie,Carmen M Zainea,Olga V Bugrova,Demin Aa,Olga Ershova,Inna A Gavrisheva,Diana G Krechikova,Gennady V Kuropatkin,Irina M Marusenko,Irina V Menshikova,Sergey M Noskov,A P Rebrov,Svetlana A Smakotina,Sergey Yakushin,Evgeny Zhilyaev,Juan Jose Amarelo Ramos,Francisco Javier Blanco Garcia,Antonio Fernandez Nebro,Silvia Perez Esteban,Juan Miguel Sanchez Burson,Raimon Sanmarti Sala,Sebnem Ataman,Sami Hizmetli,Omer Kuru,Karen M J Douglas,Paul Emery,Voon H Ong,Thomas P Sheeran,Rafat Y Faraawi,Clode Lessard,Carlos Abud Mendoza,Hilario Ernesto Avila-Armengol,Francisco I Avila Zapata,Fedra Irazoque-Palazuelos,Marco Antonio Maradiaga Cecena,César Pacheco-Tena,Juan C Rizo-Rodriguez,Isaura M Rodriguez-Torres,Jacob A Aelion,Barbara A Caciolo,James M Calmes,Prem Chatpar,Nimesh Dayal,Alex De Jesus,Ara Dikranian,Erdal Diri,Michael J Fairfax,Ira F Fenton,Roy Fleischmann,Norman Gaylis,Ronald L George,Dale G Halter,Paul Hernandez,Susan A Hole,Antony C Hou,John P Huff,Suzanne Kafaja,Alastair C Kennedy,Howard Kenney,Steven C. Kimmel,Brian S Kirby,Clarence W Legerton,Stephen M Lindsey,Jyothi R. Mallepalli,Steven D Mathews,Samy K Metyas,Wesley T Mizutani,Sabeen Najam,João Nascimento,Shirley W Pang,Rakesh C Patel,Jeffrey E Poiley,Carlos E Ramirez,Riteesha Reddy,Qaiser Rehman,William M Schnitz,Craig D. Scoville,William J Shergy,Joel C Silverfield,Atul Singhal,Yvonne R Smallwood-Sherrer,Suthin N Songcharoen,Michael T. Stack,William Stohl,Tien-I K Su,James Udell,Saleem Waraich,Charles E Weidmann,Nathan Wei,Craig W Wiesenhutter,Anne E Winkler,Karen E Zagar,Alberto Berman,Eduardo Mysler,Rodolfo A Pardo Hidalgo,Horacio O Venarotti,Irmgadt Annelise Goecke Sariego,Renato E Jimenez Calabresse,Juan Ignacio Vargas Ruiz-Tagle,Luis Vargas,Alfredo E Berrocal,Manuel Gustavo Leon Portocarrero,Felix Jesus,Romero Pena +212 more
TL;DR: Tofacitinib monotherapy was not shown to be non-inferior to either combination of adalimumab and methotrexate, and no new or unexpected safety issues were reported for either treatment in this study for up to 1 year.
Journal ArticleDOI
Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial
Peter Nash,Bruce Kirkham,Masato Okada,Proton Rahman,B. Combe,Gerd Burmester,David H. Adams,Lisa Kerr,Chin Lee,Catherine L Shuler,Mark C. Genovese,Khalid Ahmed,Jeffrey Alper,Nichol Barkham,Ralph E. Bennett,Francisco Javier Blanco Garcia,Ricardo Blanco Alonso,Howard B. Blumstein,Michael S. Brooks,Gerd R Burmester,Patricia Cagnoli,Paul H. Caldron,Alain Cantagrel,Der Yuan Chen,Melvin Churchill,Christine E Codding,Peter M.G. Deane,Jose Del Giudice,Atul Deodhar,Rajat K. Dhar,Eva Dokoupilova,Rita M. Egan,Andrea Everding,Eva Galíndez,David H. Goddard,Alice B. Gottlieb,Philippe Goupille,Robert M. Griffin,Ramesh C. Gupta,Stephen B. Hall,Kalpita Hatti,Mary P. Howell,Yu-Huei Huang,Ramina Jajoo,Namieta M. Janssen,Uta Kiltz,Alan Kivitz,Steven J. Klein,Mariusz P. Korkosz,Roshan Kotha,Joel M. Kremer,Cummins Lue,José Luis Marenco de la Fuente,Helena Marzo-Ortega,Jordi Gratacós Masmitjà,Philip J. Mease,Pier Luigi Meroni,Eric C. Mueller,Anupama C. Nandagudi,Antonio Fernández-Nebro,Clark M. Neuwelt,Ana Maria Orbai,Meera R. Oza,Deborah L. Parks,Debendra Pattanaik,Maria Rell-Bakalarska,David H. Rosmarin,Euthalia Roussou,Anna I. Rychlewska-Hanczewksa,David H. Sikes,Michael T. Stack,Prashanth Sunkureddi,Hasan Tahir,Diamant Thaçi,Tsen-Fang Tsai,Anthony M. Turkiewicz,Leonore Unger,Raúl Veiga Cabello,Ulf Wagner,Cheng Chung Wei,Alvin F. Wells,Peter Youssef,Agnieszka Zielinska +82 more
TL;DR: Both the 2-week and 4-week ixekizumab dosing regimens improved the signs and symptoms of patients with active psoriatic arthritis and who had previously inadequate response to tumour necrosis factor inhibitors, with a safety profile consistent with previous studies investigating ixeksedumab.
Journal ArticleDOI
Proinflammatory properties of the human S100 protein S100A12
TL;DR: Human S100A12 induced migration of monocytoid cells, with optimal activity at 10−10 M and potency of >10−9 M C5a, and may contribute to leukocyte migration in chronic inflammatory responses.
Journal ArticleDOI
Extent of disease on high-resolution computed tomography lung is a predictor of decline and mortality in systemic sclerosis-related interstitial lung disease
O. Moore,Nicole S L Goh,Tamera J. Corte,Hannah Rouse,Oliver Hennessy,Vivek Thakkar,J. Byron,Joanne Sahhar,Janet Roddy,Eli Gabbay,Peter Youssef,Peter Nash,Jane Zochling,Susanna Proudman,Susanna Proudman,Wendy Stevens,Mandana Nikpour,Mandana Nikpour +17 more
TL;DR: Extensive disease (>20%) on HRCT at baseline, reported using a semi-quantitative grading system, is associated with a three-fold increased risk of deterioration or death in SSc-ILD, compared with limited disease.