P
Petr Halada
Researcher at Academy of Sciences of the Czech Republic
Publications - 185
Citations - 4536
Petr Halada is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Proteome & Pyranose. The author has an hindex of 34, co-authored 179 publications receiving 3987 citations. Previous affiliations of Petr Halada include Charles University in Prague & University of Agricultural Sciences, Dharwad.
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Journal ArticleDOI
Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens
Peter R. Jungblut,Ulrich E. Schaible,Hans-Joachim Mollenkopf,Ursula Zimny-Arndt,Bärbel Raupach,Jens Mattow,Petr Halada,Stephanie Lamer,Kristine Hagens,Stefan H. E. Kaufmann +9 more
TL;DR: It is to be hoped that the availability of the mycobacterial proteome will facilitate the design of novel measures for prevention and therapy of one of the great health threats, tuberculosis.
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C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances
Petr Müller,Eva Ruckova,Petr Halada,Philip J. Coates,Roman Hrstka,David P. Lane,Borek Vojtesek +6 more
TL;DR: The data identify C-terminal phosphorylation of Hsp70 and Hsp90 as a switch for regulating co-chaperone binding and indicate that cancer cells possess an elevated protein folding environment by the concerted action of co-Chaperone expression and chaperone modifications.
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Hepcidin, the hormone of iron metabolism, is bound specifically to α-2-macroglobulin in blood
Gabriela Peslova,Jiri Petrak,Katerina Kuzelova,Ivan Hrdy,Petr Halada,Philip W. Kuchel,Shan Soe-Lin,Prem Ponka,Robert Sutak,Erika M. Becker,Michael L.-H. Huang,Yohan Suryo Rahmanto,Des R. Richardson,Daniel Vyoral,Daniel Vyoral +14 more
TL;DR: The demonstration that alpha2-M is the hePCidin transporter could lead to better understanding of hepcidin physiology, methods for its sensitive measurement and the development of novel drugs for the treatment of iron-related diseases.
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Characteristics of Gloeophyllum trabeum Alcohol Oxidase, an Extracellular Source of H2O2 in Brown Rot Decay of Wood
TL;DR: The extracellular distribution and the enzyme's abundance and preference for methanol, potentially available from the demethylation of lignin, all point to a possible role for AOX as a major source of H2O2, a component of Fenton's reagent implicated in the generally accepted mechanisms for brown rot through the production of highly destructive hydroxyl radicals.
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Discovery of a Chlorophyll Binding Protein Complex Involved in the Early Steps of Photosystem II Assembly in Synechocystis
Jana Knoppová,Jana Knoppová,Roman Sobotka,Roman Sobotka,Martin Tichý,Martin Tichý,Jianfeng Yu,Peter Konik,Petr Halada,Peter J. Nixon,Josef Komenda,Josef Komenda +11 more
TL;DR: A chlorophyll and β-carotene binding protein complex in the cyanobacterium Synechocystis PCC 6803 important for formation of the D1/D2 reaction center assembly complex is identified.