Phb Willemse

TL;DR: It was determined that tumor size associated with improved survival was less than 1 cm, and the single-day regimen was considered preferable for future use because the toxicity was lower and CP treatment required shorter hospitalization.

TL;DR: RhIL-6 can be administered with controllable side effects in this setting, up to and including a SC dose of 10 micrograms/kg/d on an outpatient basis, and has a promising stimulating effect on leukopoiesis and thrombopoiedis.

TL;DR: Combination chemotherapy with cisplatin can enhance survival by more than 10% at 5 and 10 years compared with the best treatment of the precisplatin era: Hexa-CAF.

TL;DR: This article reports on the statements written by the chairmen and approved by the consensus group, which achieved consensus on a number of issues with implications for standard practice and for research.

TL;DR: An overview of the TRAIL pathway, the physiological role of TRAIL and the factors regulating TRAIL sensitivity are provided and the clinical development of novel agents, i.e. rhTRAIL and agonistic antibodies, that activate the death receptors are discussed.