Philippe Terrier

TL;DR: This report presents a case of hibernoma of the thigh whose the diagnosis initially suggested that it was a mixed liposarcoma with myxoid and well differentiated components.

TL;DR: Surgical excision of lung metastases should remain the treatment of choice, if preoperative evaluation indicates that complete clearance of the metastases is possible and complete surgery remains the cornerstone of the treatment with best results for low grade sarcomatosis.

TL;DR: The cumulative probabilities of local (LR) and of metastatic (MR) relapse with death as a competing event and the outcomes of interest were 3369 adult patients with localized STS from January 1990 to December 2009.

TL;DR: Leiomyosarcomas (LMS) are currently treated as a single entity but are now identified as a transcriptionally, genomically and clinically homogeneous subgroup of LMS, whose oncogenesis is driven by the acquisition of high differentiation through MYOCD over-expression, which confers them sensitivity toMYOCD/SRF inhibitors, which could thus become a potential therapeutic target.

TL;DR: Patients who progressed after 1–2 chemotherapy lines received High-dose ifosfamide (HDI) in the form of 4 g/m2 daily (over 24 hours CI) for 3 days for a total dose of 12 g/ m2; cycles were given with growth factor support and were repeated every 3 weeks.