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Phillip Young
Researcher at Waters Corporation
Publications - 7
Citations - 773
Phillip Young is an academic researcher from Waters Corporation. The author has contributed to research in topics: Solvation & Ab initio. The author has an hindex of 7, co-authored 7 publications receiving 751 citations. Previous affiliations of Phillip Young include University of Manchester.
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Journal ArticleDOI
Quantitative proteomic analysis by accurate mass retention time pairs.
Jeffrey C. Silva,Richard Denny,Craig A. Dorschel,Marc V. Gorenstein,Ignatius J. Kass,Guo-Zhong Li,Therese McKenna,Michael J. Nold,Keith Richardson,Phillip Young,Scott J. Geromanos +10 more
TL;DR: The principal focus of this paper will demonstrate the quantitative aspects of the methodology and continue with a discussion of the associated, complementary qualitative capabilities.
Journal ArticleDOI
Tautomeric equilibria in 2-hydroxypyridine and in cytosine. An assessment of density functional methods, including gradient corrections
TL;DR: In this paper, the free energy differences between the enol and keto tautomers of 2-hydroxypyridine and of cytosine were calculated employing density functional techniques including gradient corrections.
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Hydration free energies of nucleic acid bases using an ab initio continuum model
Phillip Young,Ian H. Hillier +1 more
TL;DR: The self-consistent reaction field model, implemented within an ab initio MO framework, predicts the relative solvation energies of four methylated nucleic acid bases in close agreement with OPLS FEP calculations, in contrast to AMBER FEP results and the predictions of the semi-empirical AM1-SM2 method as mentioned in this paper.
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ProbSeq—A Fragmentation Model for Interpretation of Electrospray Tandem Mass Spectrometry Data
John Skilling,Richard Denny,Keith Richardson,Phillip Young,Therese McKenna,Iain Campuzano,Mark Ritchie +6 more
TL;DR: In this paper, a probabilistic peptide fragmentation model for use in protein databank searching and de novo sequencing of electrospray tandem mass spectrometry data is described.
Journal Article
ProbSeq - a fragmentation model for interpretation of electrospray tandem mass spectrometry data : Proteins and Signals
John Skilling,Richard Denny,Keith Richardson,Phillip Young,Therese McKenna,Lain Campuzano,Mark Ritchie +6 more
TL;DR: A probabilistic peptide fragmentation model for use in protein databank searching and de novo sequencing of electrospray tandem mass spectrometry data is described and preliminary results of tuning efforts are presented.