Michael J. Nold

TL;DR: The principal focus of this paper will demonstrate the quantitative aspects of the methodology and continue with a discussion of the associated, complementary qualitative capabilities.

TL;DR: It is shown that native CSP is N-terminally processed in the mosquito host and undergoes a reversible conformational change to mask some epitopes in the N- and C-terminal domains until the sporozoite interacts with the liver hepatocyte.

TL;DR: The data reveal a novel mechanism whereby prodynorphin-derived peptides facilitate NMDAR function and produce neurotoxicity and suggest that synthetic peptides that bind DYNp, thus preventing their interaction with N MDAR, may be novel therapeutic agents for the treatment of spinal cord injury.

TL;DR: An integrated approach has demonstrated the significant role of the merozoite proteome during erythrocyte invasion, while identifying numerous unknown proteins likely to be involved in invasion.

TL;DR: In this paper, the authors proposed a hybrid data independent acquisition (DIA) and data dependent acquisition approach for mass spectrometer data acquisition, which can provide a hybrid DIA and DDA approach.