P
Phoonsuk Limraksasin
Researcher at Tohoku University
Publications - 14
Citations - 73
Phoonsuk Limraksasin is an academic researcher from Tohoku University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 4 publications receiving 21 citations.
Papers
More filters
Journal ArticleDOI
In Vitro Fabrication of Hybrid Bone/Cartilage Complex Using Mouse Induced Pluripotent Stem Cells.
Phoonsuk Limraksasin,Takeru Kondo,Maolin Zhang,Hiroko Okawa,Hiroko Okawa,Thanaphum Osathanon,Prasit Pavasant,Hiroshi Egusa +7 more
TL;DR: It is suggested that combined use of micro-space culture and mechanical stimuli facilitates hybrid bone/Cartilage tissue formation from iPSCs, and that the bone/cartilage tissue ratio in iPSC constructs could be manipulated through the induction protocol.
Journal ArticleDOI
Shaking culture enhances chondrogenic differentiation of mouse induced pluripotent stem cell constructs.
Phoonsuk Limraksasin,Yukihiro Kosaka,Maolin Zhang,Naohiro Horie,Takeru Kondo,Takeru Kondo,Hiroko Okawa,Masahiro Yamada,Hiroshi Egusa +8 more
TL;DR: Shaking culture activates TGF-β expression and Wnt signaling to promote chondrogenic differentiation in mouse iPSCs in vitro, and could provide a promising strategy for iPSC-based cartilage bioengineering for study of disease mechanisms and new therapies.
Journal ArticleDOI
Size-Optimized Microspace Culture Facilitates Differentiation of Mouse Induced Pluripotent Stem Cells into Osteoid-Rich Bone Constructs.
Phoonsuk Limraksasin,Hiroko Okawa,Hiroko Okawa,Maolin Zhang,Takeru Kondo,Thanaphum Osathanon,Prasit Pavasant,Hiroshi Egusa +7 more
TL;DR: Elp500 microspace culture specifically induces mouse iPSCs into osteoid-rich bone-like tissue possessing high bone regeneration capacity and suggests that microspace size affects self-organized osteogenic differentiation of iPSC.
Journal ArticleDOI
Novel Mesenchymal Stem Cell Spheroids with Enhanced Stem Cell Characteristics and Bone Regeneration Ability
Yumi Ohori-Morita,Kunimichi Niibe,Phoonsuk Limraksasin,Praphawi Nattasit,Xinchao Miao,Masahiro Yamada,Yo Mabuchi,Yumi Matsuzaki,Hiroshi Egusa +8 more
TL;DR: It is suggested that NM-spheroids generated using modified neurosphere culture conditions under continuous shaking recovered their stem cell characteristics in vitro and enhanced bone regeneration in vivo, which should have great clinical potential for bone and tissue regenerative therapies as a stem cell-based biomaterial therapy.
Journal ArticleDOI
Intermittent compressive force induces cell cycling and reduces apoptosis in embryoid bodies of mouse induced pluripotent stem cells
Jeeranan Manokawinchoke,Phoonsuk Limraksasin,Hiroko Okawa,Prasit Pavasant,Hiroshi Egusa,Thanaphum Osathanon +5 more
TL;DR: In this article , a molecular mechanism in induced pluripotent stem cells (iPSCs) responding to intermittent compressive force (ICF) was identified by analyzing the global gene expression profile.