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Pier L. Meroni

Researcher at University of Milan

Publications -  18
Citations -  499

Pier L. Meroni is an academic researcher from University of Milan. The author has contributed to research in topics: Antiphospholipid syndrome & Beta 2-Glycoprotein I. The author has an hindex of 7, co-authored 18 publications receiving 479 citations.

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Statins prevent endothelial cell activation induced by antiphospholipid (anti–β2-glycoprotein I) antibodies: Effect on the proadhesive and proinflammatory phenotype

TL;DR: Endothelial activation mediated by anti-beta2GPI antibody can be inhibited by statins, and this data provide a rationale for using statins as an additional therapeutic tool in APS.
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Inflammation and Accelerated Atherosclerosis: Basic Mechanisms

TL;DR: The studies described support a role for immunologic-inflammatory mechanisms in the pathogenesis of atherosclerosis, which is evident in many autoimmune diseases, but also in the general population lacking an overt autoimmune disease.
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Antibodies to endothelial cells identify myocardial damage and predict development of coronary artery disease in patients with transplanted hearts.

TL;DR: The significant association of anti-endothelial antibodies with cellular infiltrates, depletion of vascular antithrombin and myocardial damage suggests a role for antibody in the development of transplant-induced arteriopathy.