P
Pierre Jouannet
Researcher at Paris Descartes University
Publications - 53
Citations - 3953
Pierre Jouannet is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Sperm & Semen. The author has an hindex of 23, co-authored 53 publications receiving 3719 citations. Previous affiliations of Pierre Jouannet include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Male reproductive health and environmental xenoestrogens
Jorma Toppari,John Chr. Larsen,Peter Christiansen,Aleksander Giwercman,Philippe Grandjean,Louis J. Guillette,Bernard Jégou,Tina Kold Jensen,Pierre Jouannet,Niels Keiding,Henrik Leffers,John A. McLachlan,Otto A. Meyer,Jørn Müller,E. Rajpert-De Meyts,Thomas H. Scheike,Richard M. Sharpe,John P. Sumpter,Niels E. Skakkebæk +18 more
TL;DR: The growing number of reports demonstrating that common environmental contaminants and natural factors possess estrogenic activity presents the working hypothesis that the adverse trends in male reproductive health may be, at least in part, associated with exposure to estrogenic or other hormonally active environmental chemicals during fetal and childhood development.
Journal ArticleDOI
Time to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European cities
Rémy Slama,Francis Eustache,Béatrice Ducot,Tina Kold Jensen,Niels Jørgensen,Antero Horte,S. Irvine,J. Suominen,Anne-Grethe Andersen,Jacques Auger,Matti Vierula,Jorma Toppari,Anders Nyboe Andersen,Niels Keiding,N E Skakkebaek,Alfred Spira,Pierre Jouannet +16 more
TL;DR: The results highlight the importance of sperm morphology parameters and indicate that the effect of proportion of normal sperm on TTP may be independent of sperm concentration.
Journal ArticleDOI
Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men
Céline Chalas Boissonnas,Hafida El abdalaoui,Virginie Haelewyn,Patricia Fauque,Patricia Fauque,Jean Michel Dupont,Jean Michel Dupont,Ivo Gut,Daniel Vaiman,Daniel Vaiman,Pierre Jouannet,Jörg Tost,Hélène Jammes,Hélène Jammes,Hélène Jammes +14 more
TL;DR: This study demonstrates that epigenetic perturbations of the 6th CTCF site of the H19 DMR might be a relevant biomarker for quantitative defects of spermatogenesis in humans and defined a methylation threshold sustaining the classification of patients in two groups, unmethylated and methylated.
Journal ArticleDOI
Assisted Reproductive Technology affects developmental kinetics, H19 Imprinting Control Region methylation and H19 gene expression in individual mouse embryos
Patricia Fauque,Pierre Jouannet,Corinne Lesaffre,Marie-Anne Ripoche,Luisa Dandolo,Daniel Vaiman,Daniel Vaiman,Hélène Jammes,Hélène Jammes +8 more
TL;DR: The results suggest that H19 could be used as a sensor of the epigenetic disturbance of the utilized techniques, with a striking effect of each manipulation associated to ART practices.
Journal ArticleDOI
Sperm morphological defects related to environment, lifestyle and medical history of 1001 male partners of pregnant women from four European cities
Jacques Auger,Francis Eustache,Anne-Grethe Andersen,D. S. Irvine,Niels Jørgensen,N E Skakkebaek,J. Suominen,Jorma Toppari,Matti Vierula,Pierre Jouannet +9 more
TL;DR: The present study indicated that the detailed assessment of sperm abnormalities is a useful biomarker of the effect of various external factors which may qualitatively affect human spermatogenesis.