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Pierre-Pascal Lenck-Santini

Researcher at University of Vermont

Publications -  44
Citations -  2999

Pierre-Pascal Lenck-Santini is an academic researcher from University of Vermont. The author has contributed to research in topics: Place cell & Hippocampal formation. The author has an hindex of 27, co-authored 43 publications receiving 2665 citations. Previous affiliations of Pierre-Pascal Lenck-Santini include Aix-Marseille University & Centre national de la recherche scientifique.

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Role of interictal epileptiform abnormalities in cognitive impairment

Gregory L. Holmes, +1 more
- 01 May 2006 - 
TL;DR: It is suggested that interictal spikes, particularly if frequent and widespread, can impair cognitive abilities, through interference with waking learning and memory, and memory consolidation during sleep.
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Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex

Vincent Hok, +3 more
- 22 Mar 2005 - 
TL;DR: It is shown that firing activity of neurons in medial prefrontal cortex (mPFC) reflects the motivational salience of places, and is suggested that mPFC neurons might be responsible for encoding the rat's goals, a process necessary for path planning.
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Goal-related activity in hippocampal place cells.

Vincent Hok, +5 more
- 17 Jan 2007 - 
TL;DR: It is proposed that place cells provide both a geometric representation of the current environment and a reflection of the rat's expectancy that it is located correctly at the goal, and may participate in a neural network allowing the rat to plan accurate trajectories in space.
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Hippocampal interictal epileptiform activity disrupts cognition in humans

Jonathan K. Kleen, +7 more
- 02 Jul 2013 - 
TL;DR: Hippocampal IED in humans may disrupt memory maintenance and retrieval, but not encoding, and this study strengthens the argument that IED may contribute to cognitive impairment in epilepsy depending upon when and where they occur.
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Attention-Like Modulation of Hippocampus Place Cell Discharge

André A. Fenton, +14 more
- 31 Mar 2010 - 
TL;DR: The hippocampus place code is concluded to be a dynamic representation of the spatial information in the immediate focus of attention, implying that a covert, dynamic attention-like process modulates discharge on a ∼1 s time scale.