P
Pilar Pizcueta
Researcher at University of Barcelona
Publications - 51
Citations - 2560
Pilar Pizcueta is an academic researcher from University of Barcelona. The author has contributed to research in topics: Portal hypertension & Portal venous pressure. The author has an hindex of 25, co-authored 48 publications receiving 2477 citations. Previous affiliations of Pilar Pizcueta include Wellcome Trust.
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Journal ArticleDOI
Pathophysiology of portal hypertension.
TL;DR: An expanded plasma volume is observed in all forms of portal hypertension, due to renal sodium retention, which has been shown to precede the increase in cardiac output and can be prevented or reversed by sodium restriction and spironolactone.
Journal ArticleDOI
Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition.
Pilar Pizcueta,Pilar Pizcueta,Josep M. Piqué,Josep M. Piqué,Mercedes Fernandez,Mercedes Fernandez,Jaime Bosch,Jaime Bosch,Joan Rodés,Joan Rodés,Brendan J.R. Whittle,Brendan J.R. Whittle,Salvador Moncada,Salvador Moncada +13 more
TL;DR: The concept that local excess formation of NO contributes to changes in splanchnic circulation associated with portal hypertension in cirrhosis in rats with cirrhotic rats is supported.
Journal ArticleDOI
Enhancement of portal pressure reduction by the association of isosorbide-5-mononitrate to propranolol administration in patients with cirrhosis
TL;DR: Study results indicate that isosorbide‐5‐mononitrate enhances the beneficial effects of propranolol on portal hypertension in patients with cirrhosis.
Journal ArticleDOI
CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1.
Margarita Martin,Xavier Romero,Miguel Angel de la Fuente,Victoria Tovar,Nuria Zapater,Enric Esplugues,Pilar Pizcueta,Jaime Bosch,Pablo Engel +8 more
TL;DR: Concurrent ligation of human CD84 with mAbs or CD84-Ig and CD3 enhanced IFN-γ secretion in human lymphocytes and acts as a costimulatory molecule.
Journal ArticleDOI
Effects of blood volume restitution following a portal hypertensive-related bleeding in anesthetized cirrhotic rats
Beatriz Castañeda,J. C. Morales,Raffaella Lionetti,Eduardo Moitinho,Victoria Andreu,Sofía Pérez-del-Pulgar,Pilar Pizcueta,Juan Rodés,Jaime Bosch +8 more
TL;DR: It is concluded that a transfusion policy aimed at completely replacing blood loss worsens the magnitude of bleeding and mortality from portal hypertensive‐related bleeding in cirrhotic rats and on the contrary, moderate blood transfusion allowed hemodynamic stabilization and increased survival.