P
Ping-Chung Leung
Researcher at The Chinese University of Hong Kong
Publications - 532
Citations - 16998
Ping-Chung Leung is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Osteoporosis & Bone mineral. The author has an hindex of 58, co-authored 513 publications receiving 14930 citations.
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Journal ArticleDOI
Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
Dennis M. Black,Pierre D. Delmas,Richard Eastell,Ian R. Reid,Steven Boonen,Jane A. Cauley,Felicia Cosman,Peter L. Lakatos,Ping-Chung Leung,Z. Man,Carlos Mautallen,Peter Mesenbrink,Huilin Hu,John Caminis,Karen Tong,Theresa Rosario-Jansen,Joel S. Krasnow,Trisha F. Hue,Deborah E. Sellmeyer,Erik Fink Eriksen,Steven R. Cummings +20 more
TL;DR: A once-yearly infusion of zoledronic acid during a 3-year period significantly reduced the risk of vertebral, hip, and other fractures and was associated with a significant improvement in bone mineral density and bone metabolism markers.
Journal ArticleDOI
The Effect of 3 Versus 6 Years of Zoledronic Acid Treatment of Osteoporosis: A Randomized Extension to the HORIZON-Pivotal Fracture Trial (PFT)
Dennis M. Black,Ian R. Reid,Steven Boonen,Christina Bucci-Rechtweg,Jane A. Cauley,Felicia Cosman,Steven R. Cummings,Trisha F. Hue,Kurt Lippuner,Peter L. Lakatos,Ping-Chung Leung,Z. Man,Ruvie Lou Maria Martinez,Monique Tan,Mary Ellen Ruzycky,Guoqin Su,Richard Eastell +16 more
TL;DR: Small differences in bone density and markers in those who continued versus those who stopped treatment suggest residual effects, and therefore, after 3 years of annual ZOL, many patients may discontinue therapy up to 3 years, however, vertebral fracture reductions suggest that those at high fracture risk, particularly vertebral fractures, may benefit by continued treatment.
Journal ArticleDOI
Vertebral bone mineral density, marrow perfusion, and fat content in healthy men and men with osteoporosis: dynamic contrast-enhanced MR imaging and MR spectroscopy.
James F. Griffith,David K.W. Yeung,Gregory E. Antonio,Francis K.H. Lee,Athena W. L. Hong,Samuel Y. S. Wong,Edith M. C. Lau,Ping-Chung Leung +7 more
TL;DR: Subjects with osteoporosis have decreased vertebral marrow perfusion and increased marrow fat compared with these parameters in subjects with osteopenia and subjects with normal bone density.
Journal ArticleDOI
Modified Pfirrmann grading system for lumbar intervertebral disc degeneration.
James F. Griffith,Yi-Xiang J. Wang,Gregory E. Antonio,Kai Chow Choi,Alfred B. Yu,Anil T. Ahuja,Ping-Chung Leung +6 more
TL;DR: The modified Pfirrmann grading system is useful at discriminating severity of disc degeneration in elderly subjects and can be applied with good intra- and interobserver agreement.
Journal ArticleDOI
Immunomodulatory and anti-SARS activities of Houttuynia cordata
Kit Man Lau,Kin Ming Lee,Chi Man Koon,Crystal S.F. Cheung,Ching Po Lau,Hei Ming Ho,Mavis Y.H. Lee,Shannon Wing-Ngor Au,Christopher H.K. Cheng,Clara Bik-San Lau,Stephen Kwok-Wing Tsui,David Chi Cheong Wan,Mary M.Y. Waye,Kam-Bo Wong,Chun K. Wong,Christopher W.K. Lam,Ping-Chung Leung,Kwok-Pui Fung +17 more
TL;DR: The present study aimed to explore the SARS-preventing mechanisms of HC in the immunological and anti-viral aspects and provided scientific data to support the efficient and safe use of HC to combat SARS.