P
Piyush Trivedi
Researcher at Rajiv Gandhi Proudyogiki Vishwavidyalaya
Publications - 124
Citations - 2146
Piyush Trivedi is an academic researcher from Rajiv Gandhi Proudyogiki Vishwavidyalaya. The author has contributed to research in topics: Quantitative structure–activity relationship & Apoptosis. The author has an hindex of 20, co-authored 120 publications receiving 1701 citations. Previous affiliations of Piyush Trivedi include Shri Govindram Seksaria Institute of Technology and Science & Poona College of Arts Science & Commerce.
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Advances in siRNA delivery in cancer therapy.
TL;DR: The barriers, potential siRNA drug delivery systems, and application of siRNA in clinical trials for cancer therapy are reviewed to harness the full potential of si RNA as a cancer therapeutic.
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Advances in Chalcones with Anticancer Activities
Chandrabose Karthikeyan,N.S.H.N. Moorthy,Sakthivel Ramasamy,Uma Vanam,Elangovan Manivannan,Devarajan Karunagaran,Piyush Trivedi +6 more
TL;DR: This review summarizes the concerted efforts expended on the design and development of anticancer chalcones recorded in recent literature and provides an overview of the patents published in this area between 2007 and 2014.
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Human CDC2-Like Kinase 1 (CLK1): A Novel Target for Alzheimer’s Disease
Princi Jain,Chandrabose Karthikeyan,N. S. Hari Narayana Moorthy,Digambar Kumar Waiker,Arvind Jain,Piyush Trivedi +5 more
TL;DR: The role of CLKs in the pathophysiology of Alzheimer's disease and therapeutic potential of targeting CLK1 in Alzheimer’s disease drug discovery and development are highlighted.
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A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma.
Xiaoyun Dai,Lingzhi Wang,Amudha Deivasigamni,Chung Yeng Looi,Chandrabose Karthikeyan,Piyush Trivedi,Arunachalam Chinnathambi,Sulaiman Ali Alharbi,Frank Arfuso,Arunasalam Dharmarajan,Boon Cher Goh,Kam M. Hui,Alan Prem Kumar,Mohd Rais Mustafa,Gautam Sethi +14 more
TL;DR: It is found that MBIC inhibited cell viability in different hepatocellular carcinoma (HCC) cell lines without exerting significant cytotoxic effects on normal liver cells, and furthermore, MBIC significantly inhibited tumor growth in an orthotopic HCC mouse model.
Journal Article
Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract.
TL;DR: The results suggest that the water soluble fraction (MTH) of herbal origin has significant analgesic and anti-inflammatory potential as reflected by the parameters investigated.