P
Popat D. Shinde
Researcher at National Chemical Laboratory
Publications - 12
Citations - 172
Popat D. Shinde is an academic researcher from National Chemical Laboratory. The author has contributed to research in topics: Methylene & Hydrobromic acid. The author has an hindex of 7, co-authored 12 publications receiving 157 citations.
Papers
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Journal ArticleDOI
Synthesis and evaluation of 4/5-hydroxy-2,3-diaryl(substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anticancer agents.
Mukund K. Gurjar,Radhika D. Wakharkar,Anu T. Singh,Jaggi Manu,Hanumant B. Borate,Popat D. Shinde,Ritu Verma,Praveen Rajendran,Sarjana Dutt,Gurvinder Singh,Vinod K. Sanna,Manoj K. Singh,Sanjay K. Srivastava,Vishal A. Mahajan,Vinod H. Jadhav,Kakali Dutta,Karthik Krishnan,Anika Chaudhary,Shiv K. Agarwal,Rama Mukherjee,Anand C. Burman +20 more
TL;DR: The data suggests that cis-restricted analogues of CA-4 are a new class of molecules that have the potential to be developed as novel agents for the treatment of cancer.
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EPZ-10 catalyzed regioselective transformation of alkenes into β-iodo ethers, iodohydrins and 2-iodomethyl-2,3-dihydrobenzofurans
TL;DR: An efficient method for the regioselective synthesis of β-iodo ethers and iodohydrines from styrene, indene and dihydronaphthalene in presence of EPZ-10R demonstrates a clean green chemical transformation with significant atom economy.
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Enzymatic kinetic resolution studies of racemic 4-hydroxycyclopent-2-en-1-one using Lipozyme IM®
Sandeep R. Ghorpade,Kulbhushan B. Bastawade,Digambar Gokhale,Popat D. Shinde,Vishal A. Mahajan,Uttam R. Kalkote,T. Ravindranathan +6 more
TL;DR: In this paper, enzymatic kinetic resolution studies of (±)-4-hydroxycyclopent-2-en-1-one were taken up in organic solvents by transesterification with vinyl acetate and alcoholysis of its acetate.
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Studies on Bromination of Active Methylene by a Mixture of Hydrobromic Acid and Hydrogen Peroxide (or TBHP)
TL;DR: In this paper, bromination of active methylene with a mixture of hydrogen peroxide or tert-butylhydroperoxide (TBHP) and hydrobromic acid is discussed.
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Li–X-type zeolite mediated Michael addition of thiols to cyclic enones and its application in the synthesis of 13-thiaprostaglandins
Popat D. Shinde,Vishal A. Mahajan,Hanumant B. Borate,Vasudha H. Tillu,Rajaram Bal,A.J. Chandwadkar,Radhika D. Wakharkar +6 more
TL;DR: In this paper, 13-Thiaprostaglandins have been synthesized in good yields using substituted hydroxycyclopentenone as the Michael acceptor and arylthiols as Michael donors.